Literature DB >> 32147010

Hybrid Therapy for Spinal Metastases.

Robert Rothrock1, Zach Pennington2, Jeff Ehresman2, Mark H Bilsky3, Ori Barzilai3, Nicholas J Szerlip4, Daniel M Sciubba5.   

Abstract

The combination of separation surgery and stereotactic body radiotherapy optimizes the treatment of metastatic spine tumors. The integration of SBRT into treatment paradigms produces superb local control rates and consequently has diminished the role of surgery from principle treatment to one of adjuvant therapy. Under this paradigm, hybrid therapy for the treatment of metastatic spine tumors employs separation surgery to decompress the spinal cord and stabilize the spine while creating a safe target for ablative SBRT. Hybrid therapy is well tolerated, allows an early return to systemic therapy, and provides durable, local tumor control compared with more aggressive traditional approaches.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Hybrid therapy; Metastases; Radiation; Radiosurgery; Separation surgery; Spinal cord; Spine; Tumor

Mesh:

Year:  2020        PMID: 32147010     DOI: 10.1016/j.nec.2019.11.001

Source DB:  PubMed          Journal:  Neurosurg Clin N Am        ISSN: 1042-3680            Impact factor:   2.509


  9 in total

1.  Medium to Long-Term Clinical Outcomes of Spinal Metastasectomy.

Authors:  Satoshi Kato; Satoru Demura; Hideki Murakami; Kazuya Shinmura; Noriaki Yokogawa; Ryohei Annen; Motoya Kobayashi; Yohei Yamada; Satoshi Nagatani; Norio Kawahara; Hiroyuki Tsuchiya
Journal:  Cancers (Basel)       Date:  2022-06-09       Impact factor: 6.575

Review 2.  Separation surgery for metastatic epidural spinal cord compression: A qualitative review.

Authors:  Giuseppe Di Perna; Fabio Cofano; Cristina Mantovani; Serena Badellino; Nicola Marengo; Marco Ajello; Ludovico Maria Comite; Giuseppe Palmieri; Fulvio Tartara; Francesco Zenga; Umberto Ricardi; Diego Garbossa
Journal:  J Bone Oncol       Date:  2020-09-26       Impact factor: 4.072

3.  Predictive factors, preventive implications, and personalized surgical strategies for bone metastasis from lung cancer: population-based approach with a comprehensive cancer center-based study.

Authors:  Xianglin Hu; Wending Huang; Zhengwang Sun; Hui Ye; Kwong Man; Qifeng Wang; Yangbai Sun; Wangjun Yan
Journal:  EPMA J       Date:  2022-01-10       Impact factor: 6.543

4.  Comprehensive surgical treatment strategy for spinal metastases.

Authors:  Arthur Wagner; Elena Haag; Ann-Kathrin Joerger; Philipp Jost; Stephanie E Combs; Maria Wostrack; Jens Gempt; Bernhard Meyer
Journal:  Sci Rep       Date:  2021-04-12       Impact factor: 4.379

5.  Surgery in Acute Metastatic Spinal Cord Compression: Timing and Functional Outcome.

Authors:  Hanno S Meyer; Arthur Wagner; Alessandra Raufer; Ann-Kathrin Joerger; Jens Gempt; Bernhard Meyer
Journal:  Cancers (Basel)       Date:  2022-04-30       Impact factor: 6.639

6.  Recommendations for stereotactic body radiation therapy for spine and non-spine bone metastases. A GETUG (French society of urological radiation oncolgists) consensus using a national two-round modified Delphi survey.

Authors:  F Vilotte; D Pasquier; P Blanchard; S Supiot; J Khalifa; U Schick; T Lacornerie; L Vieillevigne; D Marre; O Chapet; I Latorzeff; N Magne; E Meyer; K Cao; Y Belkacemi; J E Bibault; M Berge-Lefranc; J C Faivre; K Gnep; V Guimas; A Hasbini; J Langrand-Escure; C Hennequin; P Graff
Journal:  Clin Transl Radiat Oncol       Date:  2022-08-08

7.  Promising clinical outcome after body gamma knife radiotherapy for mediastinal follicular dendritic cell sarcoma with thoracic spine invasion and iliac metastasis: A case report and literature review.

Authors:  Annan Hu; Ting Chen; Jian Dong
Journal:  Front Oncol       Date:  2022-09-16       Impact factor: 5.738

Review 8.  Prognostic Factors for Bone Survival and Functional Outcomes in Patients With Breast Cancer Spine Metastases.

Authors:  Rui-Qi Qiao; Hao-Ran Zhang; Rong-Xing Ma; Rui-Feng Li; Yong-Cheng Hu
Journal:  Technol Cancer Res Treat       Date:  2022 Jan-Dec

Review 9.  Surgical Metastasectomy in the Spine: A Review Article.

Authors:  Satoshi Kato; Satoru Demura; Kazuya Shinmura; Noriaki Yokogawa; Takaki Shimizu; Hideki Murakami; Norio Kawahara; Katsuro Tomita; Hiroyuki Tsuchiya
Journal:  Oncologist       Date:  2021-06-12
  9 in total

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