Literature DB >> 32146943

Personalized Approach in the Work-up and Management of Gastroesophageal Reflux Disease.

Rena Yadlapati1, John E Pandolfino2.   

Abstract

Patients with gastroesophageal reflux disease (GERD) present with heterogeneous symptoms, response to treatment, and physiologic profiles, requiring distinct and personalized management. This article provides a stepwise framework to phenotype GERD beginning with (1) characterization of symptom profile and response to acid suppression; (2) endoscopic evaluation of mucosal and anatomic integrity; (3) ambulatory reflux monitoring to characterize reflux burden and sensitivity; and (4) esophageal physiologic testing to assess gastroesophageal reflux mechanism and effectors of reflux clearance, and evaluate for alternate causes.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Esophageal manometry; Esophagitis; Functional heartburn; Hiatal hernia; Proton pump inhibitor; Reflux; Supragastric belching; Transient lower esophageal sphincter relaxation

Mesh：

Substances：

Year:  2020        PMID： 32146943      PMCID： PMC7083512          DOI： 10.1016/j.giec.2019.12.002

Source DB:  PubMed          Journal:  Gastrointest Endosc Clin N Am        ISSN： 1052-5157


  29 in total

1.  Rumination or belching-regurgitation? Differential diagnosis using oesophageal impedance-manometry.

Authors:  N Rommel; J Tack; J Arts; P Caenepeel; R Bisschops; D Sifrim
Journal:  Neurogastroenterol Motil       Date:  2009-11-25       Impact factor: 3.598

2.  Supragastric belches are the main determinants of troublesome belching symptoms in patients with gastro-oesophageal reflux disease.

Authors:  B F Kessing; A J Bredenoord; M Velosa; A J P M Smout
Journal:  Aliment Pharmacol Ther       Date:  2012-03-20       Impact factor: 8.171

3.  Limited ability of the proton-pump inhibitor test to identify patients with gastroesophageal reflux disease.

Authors:  Peter Bytzer; Roger Jones; Nimish Vakil; Ola Junghard; Tore Lind; Börje Wernersson; John Dent
Journal:  Clin Gastroenterol Hepatol       Date:  2012-07-17       Impact factor: 11.382

4.  A Randomized Double-Blind, Placebo-Controlled, Cross-Over Study Using Baclofen in the Treatment of Rumination Syndrome.

Authors:  Ans Pauwels; Charlotte Broers; Brecht Van Houtte; Nathalie Rommel; Tim Vanuytsel; Jan Tack
Journal:  Am J Gastroenterol       Date:  2017-12-05       Impact factor: 10.864

Review 5.  Addition of prokinetics to PPI therapy in gastroesophageal reflux disease: a meta-analysis.

Authors:  Li-Hua Ren; Wei-Xu Chen; Li-Juan Qian; Shuo Li; Min Gu; Rui-Hua Shi
Journal:  World J Gastroenterol       Date:  2014-03-07       Impact factor: 5.742

Review 6.  Proton Pump Inhibitor-Refractory Gastroesophageal Reflux Disease.

Authors:  Rena Yadlapati; Kelli DeLay
Journal:  Med Clin North Am       Date:  2018-11-01       Impact factor: 5.456

Review 7.  Failure of reflux inhibitors in clinical trials: bad drugs or wrong patients?

Authors:  Peter J Kahrilas; Guy Boeckxstaens
Journal:  Gut       Date:  2012-06-08       Impact factor: 23.059

8.  How many cases of laryngopharyngeal reflux suspected by laryngoscopy are gastroesophageal reflux disease-related?

Authors:  Nicola de Bortoli; Andrea Nacci; Edoardo Savarino; Irene Martinucci; Massimo Bellini; Bruno Fattori; Linda Ceccarelli; Francesco Costa; Maria Gloria Mumolo; Angelo Ricchiuti; Vincenzo Savarino; Stefano Berrettini; Santino Marchi
Journal:  World J Gastroenterol       Date:  2012-08-28       Impact factor: 5.742

Review 9.  Ambulatory reflux monitoring for diagnosis of gastro-esophageal reflux disease: Update of the Porto consensus and recommendations from an international consensus group.

Authors:  S Roman; C P Gyawali; E Savarino; R Yadlapati; F Zerbib; J Wu; M Vela; R Tutuian; R Tatum; D Sifrim; J Keller; M Fox; J E Pandolfino; A J Bredenoord
Journal:  Neurogastroenterol Motil       Date:  2017-03-31       Impact factor: 3.598

Review 10.  Meta-analysis of the efficacy of proton pump inhibitors for the symptoms of laryngopharyngeal reflux.

Authors:  C Liu; H Wang; K Liu
Journal:  Braz J Med Biol Res       Date:  2016-07-04       Impact factor: 2.590
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  4 in total

1.  Ambulatory Reflux Monitoring Guides Proton Pump Inhibitor Discontinuation in Patients With Gastroesophageal Reflux Symptoms: A Clinical Trial.

Authors:  Rena Yadlapati; Melina Masihi; C Prakash Gyawali; Dustin A Carlson; Peter J Kahrilas; Billy Darren Nix; Anand Jain; Joseph R Triggs; Michael F Vaezi; Leila Kia; Alexander Kaizer; John E Pandolfino
Journal:  Gastroenterology       Date:  2020-09-16       Impact factor: 22.682

2.  Distinct Clinical Physiologic Phenotypes of Patients With Laryngeal Symptoms Referred for Reflux Evaluation.

Authors:  Rena Yadlapati; Alexander M Kaizer; Daniel R Sikavi; Madeline Greytak; Jennifer X Cai; Thomas L Carroll; Samir Gupta; Sachin Wani; Paul Menard-Katcher; Tsung-Chin Wu; Philip Weissbrod; Andrew M Vahabzadeh-Hagh; John E Pandolfino; Walter W Chan
Journal:  Clin Gastroenterol Hepatol       Date:  2021-05-20       Impact factor: 11.382

3.  Knowledge and practice of family medicine and internal medicine residents toward the management of gastroesophageal reflux disease in Riyadh, Saudi Arabia.

Authors:  Fahad Alzahrani; Yousef Al Turki
Journal:  J Family Med Prim Care       Date:  2021-08-27

4.  Diagnostic yield and reliability of post-prandial high-resolution manometry and impedance-ph for detecting rumination and supragastric belching in PPI non-responders.

Authors:  Kelli DeLay; John E Pandolfino; Sabine Roman; C Prakash Gyawali; Edoardo Savarino; Michael Tye; Alexander Kaizer; Rena Yadlapati
Journal:  Neurogastroenterol Motil       Date:  2021-03-09       Impact factor: 3.960
  4 in total

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