Literature DB >> 32146622

Participation of Free-Radical Processes in Structural and Metabolic Disturbances in the Lung Tissues Caused by Exposure to Coal-Rock Dust and their Adaptogenic Correction.

A G Zhukova1,2, N N Mikhailova3,4, T G Sazontova5, N N Zhdanova3, A S Kazitskaya3, M S Bugaeva3, L G Gorokhova3,4, Yu V Arkhipenko5.   

Abstract

Adaptive correction of structural and metabolic disturbances in the lungs caused by longterm exposure to coal-rock dust were studied in experiments on rats. It was shown that the complex antioxidant preparation containing dihydroquercetin compensated disturbances in the redox balance in the lung tissue, prevented the formation of dust granulomas, and reduced the severity of degenerative changes in the bronchopulmonary system.

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Keywords:  adaptogen; bronchopulmonary system; coal-rock dust; dihydroquercetin; protector proteins

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Year:  2020        PMID: 32146622     DOI: 10.1007/s10517-020-04727-7

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  1 in total

1.  Pathomorphological Changes in the Brain in Dynamics of Long-Term Dust Exposure.

Authors:  M S Bugaeva; O I Bondarev; N N Mikhailova; A G Zhukova
Journal:  Bull Exp Biol Med       Date:  2021-06-26       Impact factor: 0.804

  1 in total

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