| Literature DB >> 32146511 |
Mahtab Pirouzmand1, Parya Salahshour Sani2, Zarrin Ghasemi3, Sajjad Azizi4.
Abstract
The aim of the present study was to evaluate the H2O2 scavenging activity of the ZnO2/β-CD as a biocompatible composite. Zinc peroxide was prepared via sonochemical approach. To synthesize a green composite, β-cyclodextrin was modified by citric acid (CA) and reacted with ZnO2 under ultrasonic irradiation. The prepared samples were characterized using XRD, SEM, TGA and FTIR analytical techniques. XRD analysis exhibited a typical pattern of ZnO2 and demonstrated the presence of citric acid and β-cyclodextrin in composite. The results of the catalytic assay showed that the ZnO2/CA-βCD composite displayed stronger capability to decompose H2O2 in comparison to ZnO2 particles (about seven times). It was attributed to increased adsorption capacity and solubility of composite due to the presence of citric acid and β-cyclodextrin. MTT assay studies confirmed the non-cytotoxic nature of ZnO2 particles and ZnO2/CA-βCD composite.Entities:
Keywords: Antioxidant; Biocompatible; H2O2 scavenger; Ultrasonication; ZnO2; β-Cyclodextrin
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Year: 2020 PMID： 32146511 DOI： 10.1007/s00775-020-01771-6
Source DB: PubMed Journal: J Biol Inorg Chem ISSN： 0949-8257 Impact factor: 3.358