Literature DB >> 32146277

A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg.

Junlei Li1, Wenwu Xu1, Xiao Lin2, Fang Cao1, Jiahui Yang1, Lu Li1, Xiaowei Wei1, Xiuzhi Zhang1, Dewei Zhao3, Ke Yang4.   

Abstract

Enhanced corrosion resistance and accelerated new bone formation are desired to make Mg and its alloys to be ideal candidate for bone biomaterial. For this purpose, a CDHA/MgF2 bi-layer coating was prepared on high purity Mg by a combination of fluoride treatment and hydrothermal treatment. The coating exhibited a nanoscale surface topography. Enhanced adhesion strength and corrosion resistance was obtained for the CDHA/MgF2 bi-layer coating. In vitro cell experiment showed that the adhesion, proliferation and differentiation of MG63 cells were significantly improved on Mg with CDHA/MgF2 coating compared to that on Mg with HA coating and MgF2 coating. In conclusion, this study provides a promising surface modification method for Mg metal with enhanced corrosion resistance and superior osteogenic bioactivity.
Copyright © 2020 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Biodegradable Mg; CDHA/MgF(2)bi-layer coating; Corrosion resistance; Nanorod-like morphology; Osteogenic capability

Mesh：

Substances：

Year:  2020        PMID： 32146277     DOI： 10.1016/j.colsurfb.2020.110911

Source DB:  PubMed          Journal:  Colloids Surf B Biointerfaces        ISSN： 0927-7765            Impact factor:   5.268


  3 in total

Review 1.  The advances in nanomedicine for bone and cartilage repair.

Authors:  Kai Qiao; Lu Xu; Junnan Tang; Qiguang Wang; Khoon S Lim; Gary Hooper; Tim B F Woodfield; Guozhen Liu; Kang Tian; Weiguo Zhang; Xiaolin Cui
Journal:  J Nanobiotechnology       Date:  2022-03-18       Impact factor: 10.435

2.  Immobilization of bioactive vascular endothelial growth factor onto Ca-deficient hydroxyapatite-coated Mg by covalent bonding using polydopamine.

Authors:  Junlei Li; Fang Cao; Bin Wu; Jiahui Yang; Wenwu Xu; Weidan Wang; Xiaowei Wei; Ge Liu; Dewei Zhao
Journal:  J Orthop Translat       Date:  2021-09-29       Impact factor: 5.191

3.  Evaluation of the performance of Ca-deficient hydroxyapatite (CDHA)/MgF2 bilayer coating on biodegradable high-purity magnesium in a femoral condyle defect model in rabbits.

Authors:  Shibo Huang; Junlei Li; Kairong Qin; Zhiqiang Wang; Jiahui Yang; Fang Cao; Weirong Li; Yupeng Liu; Lipeng Liu; Dewei Zhao
Journal:  Regen Biomater       Date:  2022-10-04
  3 in total

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