Literature DB >> 32144451

[Epilepsy in old age].

Kai Siebenbrodt1, Adam Strzelczyk2, Felix Rosenow2.   

Abstract

In an aging society, epilepsy in old age will become a more and more relevant disease. The diagnosis is often difficult because of the frequent occurrence of focal seizures in old age, which are easily overlooked. The diagnosis is often delayed, particularly in older patients who, for example also suffer from dementia. The causes of the epilepsy can be manifold in the aging brain. Another challenge for neurologists is the medicinal treatment of geriatric epilepsy, as many anticonvulsive drugs can be associated with serious side effects and interactions. The evidence for the effectiveness and tolerability of anticonvulsive drugs in old age is insufficient, so that the choice of drugs must be made on an individual basis. Status epilepticus is a neurological emergency, which occurs not only more frequently in older than in younger persons but is also associated with a higher mortality, so that immediate diagnosis and adequate treatment is necessary.

Entities:  

Keywords:  Anticonvulsants; Epilepsy surgery; Etiology; Semiology; Status epilepticus

Year:  2020        PMID: 32144451     DOI: 10.1007/s00115-020-00888-y

Source DB:  PubMed          Journal:  Nervenarzt        ISSN: 0028-2804            Impact factor:   1.214


  24 in total

Review 1.  Epilepsy in the elderly.

Authors:  Konrad J Werhahn
Journal:  Dtsch Arztebl Int       Date:  2009-02-27       Impact factor: 5.594

2.  Efficacy and safety of perampanel in the subgroup of elderly patients included in the phase III epilepsy clinical trials.

Authors:  Ilo E Leppik; Robert T Wechsler; Betsy Williams; Haichen Yang; Sharon Zhou; Antonio Laurenza
Journal:  Epilepsy Res       Date:  2014-12-13       Impact factor: 3.045

Review 3.  Role of neuroimaging in first seizure diagnosis.

Authors:  Candice E Crocker; Bernhard Pohlmann-Eden; Matthias H Schmidt
Journal:  Seizure       Date:  2016-06-01       Impact factor: 3.184

4.  Tolerability, safety, and efficacy of adjunctive brivaracetam for focal seizures in older patients: A pooled analysis from three phase III studies.

Authors:  Martin J Brodie; John Whitesides; Jimmy Schiemann; Joseph D'Souza; Martin E Johnson
Journal:  Epilepsy Res       Date:  2016-08-18       Impact factor: 3.045

5.  Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology.

Authors:  Robert S Fisher; J Helen Cross; Jacqueline A French; Norimichi Higurashi; Edouard Hirsch; Floor E Jansen; Lieven Lagae; Solomon L Moshé; Jukka Peltola; Eliane Roulet Perez; Ingrid E Scheffer; Sameer M Zuberi
Journal:  Epilepsia       Date:  2017-03-08       Impact factor: 5.864

6.  Epilepsy in the elderly: comparing clinical characteristics with younger patients.

Authors:  H Stefan; T W May; M Pfäfflin; C Brandt; N Füratsch; B Schmitz; B Wandschneider; R Kretz; U Runge; J Geithner; C Karakizlis; F Rosenow; F Kerling
Journal:  Acta Neurol Scand       Date:  2014-02-03       Impact factor: 3.209

7.  Population-Based Assessment of the Long-Term Risk of Seizures in Survivors of Stroke.

Authors:  Alexander E Merkler; Gino Gialdini; Michael P Lerario; Neal S Parikh; Nicholas A Morris; Benjamin Kummer; Lauren Dunn; Michael E Reznik; Santosh B Murthy; Babak B Navi; Zachary M Grinspan; Costantino Iadecola; Hooman Kamel
Journal:  Stroke       Date:  2018-04-25       Impact factor: 7.914

8.  Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984.

Authors:  W A Hauser; J F Annegers; L T Kurland
Journal:  Epilepsia       Date:  1993 May-Jun       Impact factor: 5.864

9.  Incidence and associations of poststroke epilepsy: the prospective South London Stroke Register.

Authors:  Neil S N Graham; Siobhan Crichton; Michael Koutroumanidis; Charles D A Wolfe; Anthony G Rudd
Journal:  Stroke       Date:  2013-01-31       Impact factor: 7.914

Review 10.  The causes of new-onset epilepsy and seizures in the elderly.

Authors:  Shasha Liu; Weihua Yu; Yang Lü
Journal:  Neuropsychiatr Dis Treat       Date:  2016-06-17       Impact factor: 2.570

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  2 in total

1.  Intravenous thrombolysis or mechanical thrombectomy do not increase risk of acute symptomatic seizures in patients with ischemic stroke.

Authors:  Johann Philipp Zöllner; Björn Misselwitz; Thomas Mauroschat; Christian Roth; Helmuth Steinmetz; Felix Rosenow; Adam Strzelczyk
Journal:  Sci Rep       Date:  2020-12-03       Impact factor: 4.379

Review 2.  Seizures and Epilepsy After Stroke: Epidemiology, Biomarkers and Management.

Authors:  Marian Galovic; Carolina Ferreira-Atuesta; Laura Abraira; Nico Döhler; Lucia Sinka; Francesco Brigo; Carla Bentes; Johan Zelano; Matthias J Koepp
Journal:  Drugs Aging       Date:  2021-02-23       Impact factor: 3.923

  2 in total

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