Literature DB >> 32142689

PD-1: A Driver or Passenger of T Cell Exhaustion?

Xing He1, Chenqi Xu2.   

Abstract

Okazaki and colleagues report that PD-1 signaling mainly restrains effector function at the early stage of T cell activation. The authors find that cytokine genes require strong antigen stimulation and are more susceptible to PD-1 inhibition.
Copyright © 2020 Elsevier Inc. All rights reserved.

Year:  2020        PMID: 32142689     DOI: 10.1016/j.molcel.2020.02.013

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  5 in total

1.  Numerical optimization of microfluidic vortex shedding for genome editing T cells with Cas9.

Authors:  Justin A Jarrell; Brandon J Sytsma; Leah H Wilson; Fong L Pan; Katherine H W J Lau; Giles T S Kirby; Adrian A Lievano; Ryan S Pawell
Journal:  Sci Rep       Date:  2021-06-03       Impact factor: 4.379

2.  Interferon‑stimulated gene 15 promotes progression of endometrial carcinoma and weakens antitumor immune response.

Authors:  Xiwa Zhao; Jingjing Wang; Yaojie Wang; Mengmeng Zhang; Wei Zhao; Hui Zhang; Lianmei Zhao
Journal:  Oncol Rep       Date:  2022-04-21       Impact factor: 4.136

3.  Properties and Roles of γδT Cells in Plasmodium yoelii nigeriensis NSM Infected C57BL/6 Mice.

Authors:  Hongyan Xie; Shihao Xie; Mei Wang; Haixia Wei; He Huang; Anqi Xie; Jiajie Li; Chao Fang; Feihu Shi; Quan Yang; Yanwei Qi; Zhinan Yin; Xinhua Wang; Jun Huang
Journal:  Front Cell Infect Microbiol       Date:  2022-01-20       Impact factor: 5.293

4.  Enhanced antitumor immune response in melanoma tumor model by anti-PD-1 small interference RNA encapsulated in nanoliposomes.

Authors:  Mehdi Barati; Farshad Mirzavi; Amin Reza Nikpoor; Mojtaba Sankian; Hasan Namdar Ahmadabad; Anvar Soleimani; Mohammad Mashreghi; Jalil Tavakol Afshar; Mojgan Mohammadi; Mahmoud Reza Jaafari
Journal:  Cancer Gene Ther       Date:  2021-08-02       Impact factor: 5.854

5.  In Acute Dengue Infection, High TIM-3 Expression May Contribute to the Impairment of IFNγ Production by Circulating Vδ2 T Cells.

Authors:  Eleonora Cimini; Germana Grassi; Alessia Beccacece; Rita Casetti; Concetta Castilletti; Maria Rosaria Capobianchi; Emanuele Nicastri; Chiara Agrati
Journal:  Viruses       Date:  2022-01-12       Impact factor: 5.048

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.