Literature DB >> 32142087

Highly efficient photocontrolled targeted delivery of siRNA by a cyclodextrin-based supramolecular nanoassembly.

Feng-Qing Li1, Qi-Lin Yu2, Yao-Hua Liu3, Hua-Jiang Yu3, Yong Chen1, Yu Liu1.   

Abstract

In this study, we have constructed a binary supramolecular nanoassembly composed of α-cyclodextrin-modified hyaluronic acid and an azobenzene-modified diphenylalanine derivative with a positively charged imidazole group. This nanoassembly can bind with siRNA through electrostatic interactions and efficiently delivered them into cancer cells and inhibited their growth.

Entities:  

Year:  2020        PMID： 32142087     DOI： 10.1039/d0cc00629g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Tetraethylenepentamine-Coated β Cyclodextrin Nanoparticles for Dual DNA and siRNA Delivery.

Authors:  Chi-Hsien Liu; Pei-Yin Shih; Cheng-Han Lin; Yi-Jun Chen; Wei-Chi Wu; Chun-Chao Wang
Journal:  Pharmaceutics       Date:  2022-04-23       Impact factor: 6.525

Review 2.  Hyaluronic Acid within Self-Assembling Nanoparticles: Endless Possibilities for Targeted Cancer Therapy.

Authors:  Manuela Curcio; Orazio Vittorio; Jessica Lilian Bell; Francesca Iemma; Fiore Pasquale Nicoletta; Giuseppe Cirillo
Journal:  Nanomaterials (Basel)       Date:  2022-08-18       Impact factor: 5.719

3.  Purely organic light-harvesting phosphorescence energy transfer by β-cyclodextrin pseudorotaxane for mitochondria targeted imaging.

Authors:  Fang-Fang Shen; Yong Chen; Xianyin Dai; Hao-Yang Zhang; Bing Zhang; Yaohua Liu; Yu Liu
Journal:  Chem Sci       Date:  2020-12-09       Impact factor: 9.825
  3 in total

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