BACKGROUND: A systematic review with a meta-analysis was performed to determine the prevalence and risk factors for secondary de novo adenocarcinoma in the colon used as a urinary diversion not exposed to the fecal stream. METHODS: The systematic review of the literature identified 47 patients with secondary adenocarcinoma in a colonic urinary diversion not exposed to the fecal stream. RESULTS: The diagnosis of secondary adenocarcinoma was determined due to the presence major local symptoms and because the cancer in half of the patients was detected at an advanced stage. Diagnosis at an earlier stage was associated with long-term cancer-free survival. CONCLUSIONS: The authors concluded that cystoscopy-colonoscopy screening as suggested by the American Gastroenterology Society for the general population should be applied to patients who have colon urinary diversion not exposed to the fecal stream. For patients with active high-grade inflammation, difficulty with self-catheterization, or symptoms, cystoscopy should be performed earlier. Resection of the tumor at an early stage offers better clinical outcomes with longer survival rates.
BACKGROUND: A systematic review with a meta-analysis was performed to determine the prevalence and risk factors for secondary de novo adenocarcinoma in the colon used as a urinary diversion not exposed to the fecal stream. METHODS: The systematic review of the literature identified 47 patients with secondary adenocarcinoma in a colonic urinary diversion not exposed to the fecal stream. RESULTS: The diagnosis of secondary adenocarcinoma was determined due to the presence major local symptoms and because the cancer in half of the patients was detected at an advanced stage. Diagnosis at an earlier stage was associated with long-term cancer-free survival. CONCLUSIONS: The authors concluded that cystoscopy-colonoscopy screening as suggested by the American Gastroenterology Society for the general population should be applied to patients who have colon urinary diversion not exposed to the fecal stream. For patients with active high-grade inflammation, difficulty with self-catheterization, or symptoms, cystoscopy should be performed earlier. Resection of the tumor at an early stage offers better clinical outcomes with longer survival rates.
Authors: Cemal Yazici; Patricia G Wolf; Hajwa Kim; Tzu-Wen L Cross; Karin Vermillion; Timothy Carroll; Gaius J Augustus; Ece Mutlu; Lisa Tussing-Humphreys; Carol Braunschweig; Rosa M Xicola; Barbara Jung; Xavier Llor; Nathan A Ellis; H Rex Gaskins Journal: Gut Date: 2017-02-02 Impact factor: 23.059
Authors: Susan Bullman; Chandra S Pedamallu; Ewa Sicinska; Thomas E Clancy; Xiaoyang Zhang; Diana Cai; Donna Neuberg; Katherine Huang; Fatima Guevara; Timothy Nelson; Otari Chipashvili; Timothy Hagan; Mark Walker; Aruna Ramachandran; Begoña Diosdado; Garazi Serna; Nuria Mulet; Stefania Landolfi; Santiago Ramon Y Cajal; Roberta Fasani; Andrew J Aguirre; Kimmie Ng; Elena Élez; Shuji Ogino; Josep Tabernero; Charles S Fuchs; William C Hahn; Paolo Nuciforo; Matthew Meyerson Journal: Science Date: 2017-11-23 Impact factor: 47.728
Authors: Matthew B Yurgelun; Matthew H Kulke; Charles S Fuchs; Brian A Allen; Hajime Uno; Jason L Hornick; Chinedu I Ukaegbu; Lauren K Brais; Philip G McNamara; Robert J Mayer; Deborah Schrag; Jeffrey A Meyerhardt; Kimmie Ng; John Kidd; Nanda Singh; Anne-Renee Hartman; Richard J Wenstrup; Sapna Syngal Journal: J Clin Oncol Date: 2017-01-30 Impact factor: 44.544