Literature DB >> 32139115

Intact pap2 downstream of mcr-1 appears to be required for colistin resistance.

Yujin Choi1, Ji-Young Lee1, Suk-Kyung Lim2, Kwan Soo Ko3.   

Abstract

In this study, we investigated the effect of pap2 on colistin susceptibility using intact pap2 and truncated pap2 (pap2∆351) genes, which were found along with mcr-1 in plasmid. Our experiments based on conjugation, antibiotic susceptibility testing, and time-killing assay showed that an intact pap2 gene is necessary along with mcr-1 for reduced colistin susceptibility.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Colistin resistance; mcr-1; pap2

Mesh：

Substances：

Year:  2020        PMID： 32139115     DOI： 10.1016/j.diagmicrobio.2020.114997

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  3 in total

1.  Genomic Characterization of Two Escherichia fergusonii Isolates Harboring mcr-1 Gene From Farm Environment.

Authors:  Ruishan Liu; Hao Xu; Xiaobing Guo; Shuxiu Liu; Jie Qiao; Haoyu Ge; Beiwen Zheng; Jianjun Gou
Journal:  Front Cell Infect Microbiol       Date:  2022-05-26       Impact factor: 6.073

2.  Antimicrobial resistance surveillance of Escherichia coli from chickens in the Qinghai Plateau of China.

Authors:  Biao Tang; Jingge Wang; Xue Zheng; Jiang Chang; Jiangang Ma; Juan Wang; Xiaofeng Ji; Hua Yang; Baoan Ding
Journal:  Front Microbiol       Date:  2022-07-22       Impact factor: 6.064

3.  Putative mobilized colistin resistance genes in the human gut microbiome.

Authors:  Bruno G N Andrade; Tobias Goris; Haithem Afli; Felipe H Coutinho; Alberto M R Dávila; Rafael R C Cuadrat
Journal:  BMC Microbiol       Date:  2021-07-22       Impact factor: 3.605
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.