Literature DB >> 32135143

Breakdown in the expedited partner therapy treatment cascade: from reproductive healthcare provider to the pharmacist.

Okeoma O Mmeje1, Jennifer Z Qin2, Marisa K Wetmore3, Giselle E Kolenic3, Clarissa P Diniz2, Jenell S Coleman2.   

Abstract

BACKGROUND: The rising incidence rates of sexually transmitted infections in the United States highlight the need for concurrent treatment of patients and their sexual partners. Expedited partner therapy allows healthcare providers to offer antibiotic prescriptions or medications to an index patient for distribution to their sexual partner(s) without evaluating the partner. We hypothesized that there was a gap between expedited partner therapy policy at the state level and its downstream implementation by community pharmacists.
OBJECTIVE: The objectives of our study were to evaluate pharmacists' expedited partner therapy knowledge and practices in 41 expedited partner therapy-permissible US states, to determine whether there were differences in practice based on the length of time expedited partner therapy was permissible in the state and chlamydia incidence rates, and to measure the cost of expedited partner therapy treatment. STUDY
DESIGN: A randomized cohort of pharmacists (n=335) was invited to complete a telephone interview from November 2017 through January 2018. Descriptive statistics were calculated and stratified by early, mid, and late expedited partner therapy-adopter status based on the year of the state's expedited partner therapy enactment and the state's chlamydia incidence rate. Fisher's exact test and 1-way analyses of variance were used to compare measures across strata.
RESULTS: We had 143 pharmacists (42.7%) agree to complete the survey. Among our respondents, 40.6% (n=58/143) indicated that they were aware of expedited partner therapy; 14.7% (n=21/143) reported that they had ever received an expedited partner therapy prescription, and 97% (n=139/143) reported that they would dispense an expedited partner therapy prescription if they received 1 in the future. These findings were stable across the 6 strata defined by early, mid, or late expedited partner therapy-adopter and high or low incidence rates of chlamydia status. Mean cost of azithromycin 1000 mg and cefixime 400 mg for treatment of chlamydia and gonorrhea was $22.17 (95% confidence interval, 20.29-24.05) and $30.46 (95% confidence interval, 28.65-32.26), respectively.
CONCLUSION: Fewer than one-half of the pharmacists were aware of expedited partner therapy. A small minority of pharmacists reported ever having received an expedited partner therapy prescription, regardless of the length of time expedited partner therapy had been legal in their states and the incidence of chlamydia. However, almost all pharmacists reported that they would dispense an expedited partner therapy prescription if they received 1. Additionally, costs were high for expedited partner therapy for self-pay patients. These data suggest that there are opportunities to increase expedited partner therapy utilization by healthcare providers, patients, and pharmacists.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  chlamydia; expedited partner therapy; gonorrhea; pharmacist; sexually transmitted infection; treatment and prevention

Year:  2020        PMID: 32135143     DOI: 10.1016/j.ajog.2020.02.038

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  3 in total

1.  A Statewide Mixed-Methods Study of Provider Knowledge and Behavior Administering Expedited Partner Therapy for Chlamydia and Gonorrhea.

Authors:  Emily A Groene; Christy M Boraas; M Kumi Smith; Sarah M Lofgren; Meghan K Rothenberger; Eva A Enns
Journal:  Sex Transm Dis       Date:  2022-07-04       Impact factor: 3.868

Review 2.  Special ambulatory gynecologic considerations in the era of coronavirus disease 2019 (COVID-19) and implications for future practice.

Authors:  Megan A Cohen; Anna M Powell; Jenell S Coleman; Jean M Keller; Alison Livingston; Jean R Anderson
Journal:  Am J Obstet Gynecol       Date:  2020-06-06       Impact factor: 8.661

3.  Decreasing Chlamydial Reinfections in a Female Urban Population.

Authors:  Jennifer Denise Suarez; Kristin Snackey Alvarez; Sharon Anderson; Helen King; Emily Kirkpatrick; Michael Harms; Robert Martin; Emily Adhikari
Journal:  Sex Transm Dis       Date:  2021-12-01       Impact factor: 2.830

  3 in total

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