| Literature DB >> 321348 |
Abstract
Experimental mycetoma-like lesions developed in guinea pigs after subcutaneous injection of Nocardia asteroides. Although delayed hypersensitivity appeared earlier, increased macrophage migration inhibition and microbicidal activity appeared after 7 weeks. When the lesions healed, high cell-mediated immunity was present. Cell-mediated immunity was transferred to normal recipient guinea pigs from healed donor guinea pigs by spleen cell transfer. Recipient guinea pigs showed marked protection against challenge with N. asteroides.Entities:
Mesh:
Year: 1977 PMID: 321348 PMCID: PMC421376 DOI: 10.1128/iai.15.2.370-375.1977
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441