Literature DB >> 32134481

Animal Models of Congenital Cytomegalovirus Transmission: Implications for Vaccine Development.

Hunter K Roark1, Jennifer A Jenks1, Sallie R Permar1, Mark R Schleiss2.   

Abstract

Although cytomegaloviruses (CMVs) are species-specific, the study of nonhuman CMVs in animal models can help to inform and direct research aimed at developing a human CMV (HCMV) vaccine. Because the driving force behind the development of HCMV vaccines is to prevent congenital infection, the animal model in question must be one in which vertical transmission of virus occurs to the fetus. Fortunately, two such animal models-the rhesus macaque CMV and guinea pig CMV-are characterized by congenital infection. Hence, each model can be evaluated in "proof-of-concept" studies of preconception vaccination aimed at blocking transplacental transmission. This review focuses on similarities and differences in the respective model systems, and it discusses key insights from each model germane to the study of HCMV vaccines.
© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Congenital cytomegalovirus; cytomegalovirus glycoproteins; cytomegalovirus vaccines; guinea pig cytomegalovirus; rhesus macaque cytomegalovirus

Mesh：

Substances：

Year:  2020        PMID： 32134481      PMCID： PMC7057791          DOI： 10.1093/infdis/jiz484

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  156 in total

Review 1.  Human cytomegalovirus entry into cells.

Authors:  Adam L Vanarsdall; David C Johnson
Journal:  Curr Opin Virol       Date:  2012-01-30       Impact factor: 7.090

2.  Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus.

Authors:  Scott G Hansen; Colin J Powers; Rebecca Richards; Abigail B Ventura; Julia C Ford; Don Siess; Michael K Axthelm; Jay A Nelson; Michael A Jarvis; Louis J Picker; Klaus Früh
Journal:  Science       Date:  2010-04-02       Impact factor: 47.728

3.  Congenital cytomegalovirus labyrinthitis and sensorineural hearing loss in guinea pigs.

Authors:  N K Woolf; F J Koehrn; J P Harris; D D Richman
Journal:  J Infect Dis       Date:  1989-12       Impact factor: 5.226

4.  Identification and Functional Characterization of a Novel Fc Gamma-Binding Glycoprotein in Rhesus Cytomegalovirus.

Authors:  Philipp Kolb; Steven Sijmons; Matthew R McArdle; Husam Taher; Jennie Womack; Colette Hughes; Abigail Ventura; Michael A Jarvis; Christiane Stahl-Hennig; Scott Hansen; Louis J Picker; Daniel Malouli; Hartmut Hengel; Klaus Früh
Journal:  J Virol       Date:  2019-02-05       Impact factor: 5.103

5.  Differential detection of B virus and rhesus cytomegalovirus in rhesus macaques.

Authors:  J L Huff; R Eberle; J Capitanio; S S Zhou; P A Barry
Journal:  J Gen Virol       Date:  2003-01       Impact factor: 3.891

6.  Brain and visceral involvement during congenital cytomegalovirus infection of guinea pigs.

Authors:  B P Griffith; H L Lucia; G D Hsiung
Journal:  Pediatr Res       Date:  1982-06       Impact factor: 3.756

7.  Targeted Mutagenesis of Guinea Pig Cytomegalovirus Using CRISPR/Cas9-Mediated Gene Editing.

Authors:  Craig J Bierle; Kaitlyn M Anderholm; Jian Ben Wang; Michael A McVoy; Mark R Schleiss
Journal:  J Virol       Date:  2016-07-11       Impact factor: 5.103

8.  Efficient replication of rhesus cytomegalovirus variants in multiple rhesus and human cell types.

Authors:  Anders E Lilja; Thomas Shenk
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-08       Impact factor: 11.205

9.  Human cytomegalovirus suppresses type I interferon secretion by plasmacytoid dendritic cells through its interleukin 10 homolog.

Authors:  W L William Chang; Peter A Barry; Richard Szubin; Dai Wang; Nicole Baumgarth
Journal:  Virology       Date:  2009-06-13       Impact factor: 3.616

10.  Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule.

Authors:  Cristina Bottino; Roberta Castriconi; Daniela Pende; Paola Rivera; Marina Nanni; Barbara Carnemolla; Claudia Cantoni; Jessica Grassi; Stefania Marcenaro; Nicolas Reymond; Massimo Vitale; Lorenzo Moretta; Marc Lopez; Alessandro Moretta
Journal:  J Exp Med       Date:  2003-08-11       Impact factor: 14.307
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  13 in total

1.  Murine Cytomegalovirus M25 Proteins Sequester the Tumor Suppressor Protein p53 in Nuclear Accumulations.

Authors:  Martina Dezeljin; Martin Messerle; Ivana Kutle; Katarzyna M Szymańska-de Wijs; Boris Bogdanow; Berislav Cuvalo; Lars Steinbrück; Stipan Jonjić; Karen Wagner; Rainer Niedenthal; Matthias Selbach; Lüder Wiebusch
Journal:  J Virol       Date:  2020-09-29       Impact factor: 5.103

Review 2.  Murine Models of Central Nervous System Disease following Congenital Human Cytomegalovirus Infections.

Authors:  Jerome Moulden; Cathy Yea Won Sung; Ilija Brizic; Stipan Jonjic; William Britt
Journal:  Pathogens       Date:  2021-08-21

Review 3.  The guinea pig model for tick-borne spotted fever rickettsioses: A second look.

Authors:  John V Stokes; David H Walker; Andrea S Varela-Stokes
Journal:  Ticks Tick Borne Dis       Date:  2020-08-07       Impact factor: 3.744

4.  In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome.

Authors:  Husam Taher; Eisa Mahyari; Craig Kreklywich; Luke S Uebelhoer; Matthew R McArdle; Matilda J Moström; Amruta Bhusari; Michael Nekorchuk; Xiaofei E; Travis Whitmer; Elizabeth A Scheef; Lesli M Sprehe; Dawn L Roberts; Colette M Hughes; Kerianne A Jackson; Andrea N Selseth; Abigail B Ventura; Hillary C Cleveland-Rubeor; Yujuan Yue; Kimberli A Schmidt; Jason Shao; Paul T Edlefsen; Jeremy Smedley; Timothy F Kowalik; Richard J Stanton; Michael K Axthelm; Jacob D Estes; Scott G Hansen; Amitinder Kaur; Peter A Barry; Benjamin N Bimber; Louis J Picker; Daniel N Streblow; Klaus Früh; Daniel Malouli
Journal:  PLoS Pathog       Date:  2020-11-24       Impact factor: 7.464

5.  A congenital CMV infection model for follow-up studies of neurodevelopmental disorders, neuroimaging abnormalities, and treatment.

Authors:  Yue-Peng Zhou; Meng-Jie Mei; Xian-Zhang Wang; Sheng-Nan Huang; Lin Chen; Ming Zhang; Xin-Yan Li; Hai-Bin Qin; Xiao Dong; Shuang Cheng; Le Wen; Bo Yang; Xue-Fang An; Ao-Di He; Bing Zhang; Wen-Bo Zeng; Xiao-Jun Li; Youming Lu; Hong-Chuang Li; Haidong Li; Wei-Guo Zou; Alec J Redwood; Simon Rayner; Han Cheng; Michael A McVoy; Qiyi Tang; William J Britt; Xin Zhou; Xuan Jiang; Min-Hua Luo
Journal:  JCI Insight       Date:  2022-01-11

6.  Inclusion of the Guinea Pig Cytomegalovirus Pentameric Complex in a Live Virus Vaccine Aids Efficacy against Congenital Infection but Is Not Essential for Improving Maternal and Neonatal Outcomes.

Authors:  Mark R Schleiss; Claudia Fernández-Alarcón; Nelmary Hernandez-Alvarado; Jian Ben Wang; Adam P Geballe; Michael A McVoy
Journal:  Viruses       Date:  2021-11-26       Impact factor: 5.818

7.  Engineering, decoding and systems-level characterization of chimpanzee cytomegalovirus.

Authors:  Quang Vinh Phan; Boris Bogdanow; Emanuel Wyler; Markus Landthaler; Fan Liu; Christian Hagemeier; Lüder Wiebusch
Journal:  PLoS Pathog       Date:  2022-01-04       Impact factor: 6.823

Review 8.  Understanding the interaction between cytomegalovirus and tuberculosis in children: The way forward.

Authors:  Laura Olbrich; Lisa Stockdale; Robindra Basu Roy; Rinn Song; Luka Cicin-Sain; Elizabeth Whittaker; Andrew J Prendergast; Helen Fletcher; James A Seddon
Journal:  PLoS Pathog       Date:  2021-12-09       Impact factor: 6.823

9.  KIR3DL05 and KIR3DS02 Recognition of a Nonclassical MHC Class I Molecule in the Rhesus Macaque Implicated in Pregnancy Success.

Authors:  Rachel E Nicholas; Kjell Sandstrom; Jennifer L Anderson; Willow R Smith; Molly Wetzel; Priyankana Banerjee; Sanath Kumar Janaka; David T Evans
Journal:  Front Immunol       Date:  2022-03-23       Impact factor: 8.786

Review 10.  Non-human Primate Models to Investigate Mechanisms of Infection-Associated Fetal and Pediatric Injury, Teratogenesis and Stillbirth.

Authors:  Miranda Li; Alyssa Brokaw; Anna M Furuta; Brahm Coler; Veronica Obregon-Perko; Ann Chahroudi; Hsuan-Yuan Wang; Sallie R Permar; Charlotte E Hotchkiss; Thaddeus G Golos; Lakshmi Rajagopal; Kristina M Adams Waldorf
Journal:  Front Genet       Date:  2021-07-05       Impact factor: 4.599
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