Jussi P Posti1,2,3, Jussi O T Sipilä3,4,5, Teemu M Luoto6, Päivi Rautava7,8, Ville Kytö9,10,11,12. 1. Division of Clinical Neurosciences, Department of Neurosurgery, Turku University Hospital, Turku, Finland. 2. Turku Brain Injury Centre, Turku University Hospital, Turku, Finland. 3. Department of Clinical Neurosciences, University of Turku, Finland. 4. Division of Clinical Neurosciences, Department of Neurology, Turku University Hospital, Turku, Finland. 5. Department of Neurology, Siun sote, North Karelia Central Hospital, Joensuu, Finland. 6. Department of Neurosurgery, Tampere University Hospital, Tampere University, Tampere, Finland. 7. Clinical Research Center, Turku University Hospital, Turku, Finland. 8. Department of Public Health, University of Turku, Turku, Finland. 9. Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland. 10. Heart Centre, Turku University Hospital, University of Turku, Turku, Finland. 11. Center for Population Health Research, Turku University Hospital, University of Turku, Turku, Finland. 12. Administative Center, Hospital District of Southwest Finland, Turku, Finland.
Abstract
BACKGROUND: we investigated trends of traumatic brain injury (TBI)-related hospitalisations, deaths, acute neurosurgical operations (ANO), and lengths of hospital stay (LOS) in patients aged ≥70 years in Finland using a population-based cohort. METHODS: nationwide databases were searched for all admissions with a TBI diagnosis as well as later deaths for persons ≥70 years of age during 2004-2014. RESULTS: the study period included 20,259 TBI-related hospitalisations (mean age = 80.7 years, men = 48.9%). The incidence of TBI-related hospitalisations was 283/100,000 person-years with an estimated overall annual increase of 2.9% (95% CI: 0.4-5.9%). There was an annual decrease of 2.2% in in-hospital mortality (IHM) in men (95% CI: 0.1-4.3%), with no change in women or overall. There was an annual decrease of 1.1% in odds for ANOs among hospitalised overall (95% CI: 0.1-2.1%) and of 1.4% in men (95% CI: 0.0-2.7%), while no change was observed in women. LOS decreased annually by 2.5% (95% CI: 2.1-2.9%). The incidence of TBI-related deaths was 70/100,000 person-years with an estimated annual increase of 1.6% in women (95% CI: 0.2-2.9%), but no change in men or overall. Mean ages of TBI-related admissions and deaths increased (P < 0.001). INTERPRETATION: the incidence rate of geriatric TBI-related hospitalisations increased, especially in women, but LOS and the rate of ANOs among hospitalised decreased. The overall TBI-related mortality remained stable, and IHM decreased in men, while in women, the overall mortality increased and IHM remained stable. However, the overall incidence rates of TBI-related hospitalisations and deaths and the number of cases of IHM were still higher in men.
BACKGROUND: we investigated trends of traumatic brain injury (TBI)-related hospitalisations, deaths, acute neurosurgical operations (ANO), and lengths of hospital stay (LOS) in patients aged ≥70 years in Finland using a population-based cohort. METHODS: nationwide databases were searched for all admissions with a TBI diagnosis as well as later deaths for persons ≥70 years of age during 2004-2014. RESULTS: the study period included 20,259 TBI-related hospitalisations (mean age = 80.7 years, men = 48.9%). The incidence of TBI-related hospitalisations was 283/100,000 person-years with an estimated overall annual increase of 2.9% (95% CI: 0.4-5.9%). There was an annual decrease of 2.2% in in-hospital mortality (IHM) in men (95% CI: 0.1-4.3%), with no change in women or overall. There was an annual decrease of 1.1% in odds for ANOs among hospitalised overall (95% CI: 0.1-2.1%) and of 1.4% in men (95% CI: 0.0-2.7%), while no change was observed in women. LOS decreased annually by 2.5% (95% CI: 2.1-2.9%). The incidence of TBI-related deaths was 70/100,000 person-years with an estimated annual increase of 1.6% in women (95% CI: 0.2-2.9%), but no change in men or overall. Mean ages of TBI-related admissions and deaths increased (P < 0.001). INTERPRETATION: the incidence rate of geriatric TBI-related hospitalisations increased, especially in women, but LOS and the rate of ANOs among hospitalised decreased. The overall TBI-related mortality remained stable, and IHM decreased in men, while in women, the overall mortality increased and IHM remained stable. However, the overall incidence rates of TBI-related hospitalisations and deaths and the number of cases of IHM were still higher in men.
Authors: Rahul A Sastry; Josh R Feler; Belinda Shao; Rohaid Ali; Lynn McNicoll; Albert E Telfeian; Adetokunbo A Oyelese; Robert J Weil; Ziya L Gokaslan Journal: PLoS One Date: 2022-10-07 Impact factor: 3.752
Authors: Elina Johansson; Teemu M Luoto; Aki Vainionpää; Anna-Maija Kauppila; Mauri Kallinen; Eija Väärälä; Eerika Koskinen Journal: Spinal Cord Date: 2020-11-04 Impact factor: 2.473