Literature DB >> 3213380

[Malignant aldosteronoma in the differential diagnosis of Conn syndrome].

B Ludvik1, B Niederle, R Roka, G Schernthaner, N Neuhold.   

Abstract

Primary aldosteronism-characterized by hypertension, hypokalemia and metabolic alkalosis--is caused by benign adenomata or bilateral adrenal hyperplasia in most cases. Aldosterone producing carcinomata of the adrenal cortex are very rare tumors. As the histological classification is difficult, the diagnosis is often drawn from tumor size, very high levels of plasma aldosterone, severe hypokalemia and malignant behaviour. The prognosis is very poor: Overall median and 5 year survival rate from diagnosis of adrenocortical carcinoma are 14 months and 24%.

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Year:  1988        PMID: 3213380

Source DB:  PubMed          Journal:  Acta Med Austriaca        ISSN: 0303-8173


  3 in total

1.  Predictors of malignancy in primary aldosteronism.

Authors:  Ayman Agha; Matthias Hornung; Igors Iesalnieks; Andreas Schreyer; Ernst Michael Jung; Assad Haneya; Hans J Schlitt
Journal:  Langenbecks Arch Surg       Date:  2013-09-19       Impact factor: 3.445

2.  Aldosterone and testosterone producing adrenal adenoma in childhood.

Authors:  K Schmitt; H Frisch; N Neuhold; G Burda; E Schober
Journal:  J Endocrinol Invest       Date:  1995-01       Impact factor: 4.256

3.  Mediator subunit Med15 dictates the conserved "fuzzy" binding mechanism of yeast transcription activators Gal4 and Gcn4.

Authors:  Lisa M Tuttle; Derek Pacheco; Linda Warfield; Damien B Wilburn; Steven Hahn; Rachel E Klevit
Journal:  Nat Commun       Date:  2021-04-13       Impact factor: 14.919

  3 in total

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