Literature DB >> 32131950

[Application of Single-cell RNA Sequencing in Research on Tumor Immune Microenvironment].

Kai Li Yang1, Zhao Sun1, Chun Mei Bai1, Lin Zhao1.   

Abstract

Tumors are highly complex systems. Understanding the compositions and functions of the tumor immune microenvironment is a prerequisite for effective tumor immunotherapy. Single-cell RNA sequencing can detect the transcriptome of a cell at the resolution of single-cell level,describe its functional status,and thus deepen the understanding of the composition and function of different cell clusters in tumor immune microenvironment. This article reviews the application of single-cell RNA sequencing in research on tumor immune microenvironment.

Entities:  

Keywords:  cell cluster; immunosuppression; single-cell RNA sequencing; tumor heterogeneity; tumor immune microenvironment

Year:  2020        PMID： 32131950     DOI： 10.3881/j.issn.1000-503X.11194

Source DB:  PubMed          Journal:  Zhongguo Yi Xue Ke Xue Yuan Xue Bao        ISSN： 1000-503X


  3 in total

Review 1.  Application and prospects of single cell sequencing in tumors.

Authors:  Ruo Han Huang; Le Xin Wang; Jing He; Wen Gao
Journal:  Biomark Res       Date:  2021-12-11

2.  An artificial intelligence method to assess the tumor microenvironment with treatment outcomes for gastric cancer patients after gastrectomy.

Authors:  Tao Chen; Xunjun Li; Qingyi Mao; Yiyun Wang; Hanyi Li; Chen Wang; Yuyang Shen; Erjia Guo; Qinglie He; Jie Tian; Mansheng Zhu; Jing Wu; Weiqi Liang; Hao Liu; Jiang Yu; Guoxin Li
Journal:  J Transl Med       Date:  2022-02-21       Impact factor: 5.531

3.  Identification of the Immune Status of Hypertrophic Cardiomyopathy by Integrated Analysis of Bulk- and Single-Cell RNA Sequencing Data.

Authors:  Wei Zhao; Tianyu Wu; Jian Zhan; Zishuang Dong
Journal:  Comput Math Methods Med       Date:  2022-10-04       Impact factor: 2.809
  3 in total

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