Sifa Marie Joelle Muchanga1,2,3, Masamitsu Eitoku1, Etongola Papy Mbelambela1, Hitoshi Ninomiya4, Tatsuo Iiyama3, Kaori Komori1, Kahoko Yasumitsu-Lovell1,5, Naomi Mitsuda1,6, Rahma Rashid Tozin2, Nagamasa Maeda7, Mikiya Fujieda6, Narufumi Suganuma1. 1. Department of Environmental Medicine, Kochi Medical School, Kochi University, Kochi, Japan. 2. Department of Obstetrics and Gynaecology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo. 3. Department of International Trials, National Center for Global Health and Medicine, Tokyo, Japan. 4. Integrated Center for Advanced Medical Technologies, Kochi Medical School, Kochi University, Kochi, Japan. 5. Gilbert Neuropsychiatry Centre, University of Gothenburg, Gothenburg, Sweden. 6. Department of Pediatrics, Kochi Medical School, Kochi University, Kochi, Japan. 7. Department of Obstetrics and Gynaecology, Kochi Medical School, Kochi University, Kochi University, Kochi, Japan.
Abstract
OBJECTIVE: Postpartum depression (PPD) is a global emotional distress that affects women and their offspring regardless of their culture. The association between nausea and vomiting of pregnancy (NVP) and PPD has been widely described only for the severe form of NVP. We aimed to assess the relationship between PPD and NVP with regards to its severity. METHODS: Data from the Japan Environment and Children's Study (JECS), a birth cohort study, were analyzed. PPD was assessed using the Edinburgh Postnatal Depression Scale (EPDS). Multiple logistic regression models were performed to assess the association between NVP and PPD. RESULTS: Out of the 80,396 women included in the study 14% had PPD. Among them 4,640 (42.1%) had mild NVP; 3,295 (29.9%) had moderate NVP whereas 1,481 (13.4%) had severe NVP. All forms of NVP were associated with PPD and the association gradually increased with the severity of NVP symptoms with odd ratio (OR): 1.26; 95% confidence interval (CI): 1.18-1.35 for mild, OR: 1.28; 95% CI: 1.19-1.38 for moderate and OR: 1.54; 95% CI: 1.42-1.68 for severe NVP. CONCLUSION: Japanese women with NVP were more susceptible to develop PPD and the more severe the NVP symptoms were, the greater the risk of PPD. Thus, close monitoring of NVP-affected women is recommended.
OBJECTIVE: Postpartum depression (PPD) is a global emotional distress that affects women and their offspring regardless of their culture. The association between nausea and vomiting of pregnancy (NVP) and PPD has been widely described only for the severe form of NVP. We aimed to assess the relationship between PPD and NVP with regards to its severity. METHODS: Data from the Japan Environment and Children's Study (JECS), a birth cohort study, were analyzed. PPD was assessed using the Edinburgh Postnatal Depression Scale (EPDS). Multiple logistic regression models were performed to assess the association between NVP and PPD. RESULTS: Out of the 80,396 women included in the study 14% had PPD. Among them 4,640 (42.1%) had mild NVP; 3,295 (29.9%) had moderate NVP whereas 1,481 (13.4%) had severe NVP. All forms of NVP were associated with PPD and the association gradually increased with the severity of NVP symptoms with odd ratio (OR): 1.26; 95% confidence interval (CI): 1.18-1.35 for mild, OR: 1.28; 95% CI: 1.19-1.38 for moderate and OR: 1.54; 95% CI: 1.42-1.68 for severe NVP. CONCLUSION: Japanese women with NVP were more susceptible to develop PPD and the more severe the NVP symptoms were, the greater the risk of PPD. Thus, close monitoring of NVP-affected women is recommended.
Entities:
Keywords:
EPDS; Postpartum depression; nausea and vomiting of pregnancy; the JECS
Authors: Renata Tambelli; Giulia Ballarotto; Carmen Trumello; Alessandra Babore Journal: Int J Environ Res Public Health Date: 2022-10-07 Impact factor: 4.614