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Literature DB >> 32130887

The Interface between Keratin Structurotype and Human Disease.

Sherif A Eldirany¹, Minh Ho¹, Christopher G Bunick².

Abstract

In this issue of Structure, Coulombe and coworkers (Lee et al., 2020) present the crystal structure of the keratin 5/14 2B heterodimeric complex containing the keratin 14 substitution C367A. The authors identify a 2B-2B contact interface important to the elongation of mature keratin 5/14 filaments.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Substances：
Keratins

Year: 2020 PMID： 32130887 PMCID： PMC7252399 DOI： 10.1016/j.str.2020.02.002

Source DB: PubMed Journal: Structure ISSN： 0969-2126 Impact factor: 5.006

10 in total

1. Keratin intermediate filament structure. Crosslinking studies yield quantitative information on molecular dimensions and mechanism of assembly.

Authors: P M Steinert; L N Marekov; R D Fraser; D A Parry
Journal: J Mol Biol Date: 1993-03-20 Impact factor: 5.469

2. Monitoring intermediate filament assembly by small-angle x-ray scattering reveals the molecular architecture of assembly intermediates.

Authors: Anna V Sokolova; Laurent Kreplak; Tatjana Wedig; Norbert Mücke; Dmitri I Svergun; Harald Herrmann; Ueli Aebi; Sergei V Strelkov
Journal: Proc Natl Acad Sci U S A Date: 2006-10-18 Impact factor: 11.205

3. Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly.

Authors: Sherif A Eldirany; Minh Ho; Alexander J Hinbest; Ivan B Lomakin; Christopher G Bunick
Journal: EMBO J Date: 2019-04-29 Impact factor: 11.598

4. Structural basis for heteromeric assembly and perinuclear organization of keratin filaments.

Authors: Chang-Hun Lee; Min-Sung Kim; Byung Min Chung; Daniel J Leahy; Pierre A Coulombe
Journal: Nat Struct Mol Biol Date: 2012-06-17 Impact factor: 15.369

5. Structure-Function Analyses of a Keratin Heterotypic Complex Identify Specific Keratin Regions Involved in Intermediate Filament Assembly.

Authors: Chang-Hun Lee; Min-Sung Kim; Shuang Li; Daniel J Leahy; Pierre A Coulombe
Journal: Structure Date: 2020-01-28 Impact factor: 5.006

6. Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses.

Authors: P A Coulombe; M E Hutton; A Letai; A Hebert; A S Paller; E Fuchs
Journal: Cell Date: 1991-09-20 Impact factor: 41.582

7. Chemical cross-linking indicates a staggered and antiparallel protofilament of desmin intermediate filaments and characterizes one higher-level complex between protofilaments.

Authors: N Geisler; J Schünemann; K Weber
Journal: Eur J Biochem Date: 1992-06-15

Review 8. Intermediate filament dynamics: What we can see now and why it matters.

Authors: Amélie Robert; Caroline Hookway; Vladimir I Gelfand
Journal: Bioessays Date: 2016-01-13 Impact factor: 4.345

9. A role for disulfide bonding in keratin intermediate filament organization and dynamics in skin keratinocytes.

Authors: Xia Feng; Pierre A Coulombe
Journal: J Cell Biol Date: 2015-04-13 Impact factor: 10.539

10. Crystal Structure of Keratin 1/10(C401A) 2B Heterodimer Demonstrates a Proclivity for the C-Terminus of Helix 2B to Form Higher Order Molecular Contacts.

Authors: Ivan B Lomakin; Alexander J Hinbest; Minh Ho; Sherif A Eldirany; Christopher G Bunick
Journal: Yale J Biol Med Date: 2020-03-27