Literature DB >> 32128598

Incomplete Excision of Cutaneous Squamous Cell Carcinoma; Systematic Review of the Literature.

Roel E Genders1, Nick Marsidi, Marlies Michi, Erik P Henny, Jelle J Goeman, Marloes S van Kester.   

Abstract

The treatment of choice for cutaneous squamous cell carcinoma is complete surgical excision. Incomplete excision of cutaneous squamous cell carcinoma has an increased risk of local recurrence, deep subclinical progression, and metastasis. This study aimed to investigate the proportion and risk factors of incomplete excised cutaneous squamous cell carcinoma. A systematic review of the literature was performed. Incomplete excision rates for cutaneous squamous cell carcinoma ranged from 0.4% to 35.7%. The pooled incomplete excision risk estimate was 13% (95% confidence interval 9-17%). Risk factors noted in more than one study for incomplete excision included tumor depth and size, type of operator, head and neck localization, and former incomplete excision. We found an overall incomplete excision rate of 13% for cutaneous squamous cell carcinoma. Risk factors should be taken into account in the management of cutaneous squamous cell carcinoma surgical treatment.

Entities:  

Keywords:  excision margin; surgery; treatment outcome; squamous cell carcinoma

Mesh:

Year:  2020        PMID: 32128598      PMCID: PMC9128936          DOI: 10.2340/00015555-3441

Source DB:  PubMed          Journal:  Acta Derm Venereol        ISSN: 0001-5555            Impact factor:   3.875


  37 in total

1.  Metastasis Risk of Cutaneous Squamous Cell Carcinoma in Organ Transplant Recipients and Immunocompetent Patients.

Authors:  Roel E Genders; Joris A J Osinga; Elise E Tromp; Peter O'Rourke; Jan N Bouwes Bavinck; Elsemieke I Plasmeijer
Journal:  Acta Derm Venereol       Date:  2018-06-08       Impact factor: 4.437

2.  Risk factors for positive margins after wide local excision of cutaneous squamous cell carcinoma.

Authors:  Thomas Jonathan Stewart; Alan Saunders
Journal:  J Dermatolog Treat       Date:  2018-02-25       Impact factor: 3.359

3.  Complete excision of nonmelanotic skin cancer: a matter of surgical experience.

Authors:  Stefan Riml; Lorenz Larcher; Peter Kompatscher
Journal:  Ann Plast Surg       Date:  2013-01       Impact factor: 1.539

Review 4.  Surgical margins of excision for basal cell carcinoma and squamous cell carcinoma.

Authors:  Conway C Huang; Sarah M Boyce
Journal:  Semin Cutan Med Surg       Date:  2004-09

5.  Cutaneous head and neck SCCs and risk of nodal metastasis - UK experience.

Authors:  Constantinos Mourouzis; Alice Boynton; Jerry Grant; Tijjani Umar; Alan Wilson; David Macpheson; Clive Pratt
Journal:  J Craniomaxillofac Surg       Date:  2009-08-27       Impact factor: 2.078

6.  Analysis of risk factors determining prognosis of cutaneous squamous-cell carcinoma: a prospective study.

Authors:  Kay D Brantsch; Christoph Meisner; Birgitt Schönfisch; Birgit Trilling; Jörg Wehner-Caroli; Martin Röcken; Helmut Breuninger
Journal:  Lancet Oncol       Date:  2008-07-09       Impact factor: 41.316

7.  Evaluation of the treatment of non-melanoma skin cancers by surgical excision.

Authors:  Vernon S C Pua; Shyamala Huilgol; Dudley Hill
Journal:  Australas J Dermatol       Date:  2009-08       Impact factor: 2.875

8.  Epidemiology of surgical treatment of nonmelanoma skin cancer of the head and neck in Greece.

Authors:  Konstantinos Seretis; Vasilios Thomaidis; Anthony Karpouzis; Dimitrios Tamiolakis; Ioannis Tsamis
Journal:  Dermatol Surg       Date:  2009-11-13       Impact factor: 3.398

9.  Non-melanoma skin cancer: United Kingdom National Multidisciplinary Guidelines.

Authors:  C Newlands; R Currie; A Memon; S Whitaker; T Woolford
Journal:  J Laryngol Otol       Date:  2016-05       Impact factor: 1.469

Review 10.  Interventions for non-metastatic squamous cell carcinoma of the skin: systematic review and pooled analysis of observational studies.

Authors:  Louise Lansbury; Fiona Bath-Hextall; William Perkins; Wendy Stanton; Jo Leonardi-Bee
Journal:  BMJ       Date:  2013-11-04
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  3 in total

1.  Keratinocyte Skin Cancers in General Surgery: The Impact of Anaesthesia, Trainee Supervision, and Choice of Reconstruction.

Authors:  William McSweeney; Matthew Leaning; Darius Dastouri
Journal:  J Skin Cancer       Date:  2021-04-13

Review 2.  Evidence from Clinical Studies Related to Dermatologic Surgeries for Skin Cancer.

Authors:  Shoichiro Ishizuki; Yoshiyuki Nakamura
Journal:  Cancers (Basel)       Date:  2022-08-08       Impact factor: 6.575

3.  Risk factors for incomplete excision of cutaneous squamous cell carcinoma: a large cohort study.

Authors:  N Marsidi; R Ottevanger; J N Bouwes Bavinck; N M A Krekel-Taminiau; J J Goeman; R E Genders
Journal:  J Eur Acad Dermatol Venereol       Date:  2022-04-20       Impact factor: 9.228

  3 in total

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