Alessio Elia1, Andreas Franz Resch2, Antonio Carlino3, Till Tobias Böhlen3, Hermann Fuchs4, Hugo Palmans5, Virgile Letellier3, Ralf Dreindl3, Jhonnatan Osorio3, Markus Stock3, David Sarrut6, Loïc Grevillot3. 1. EBG MedAustron GmbH, Marie-Curie Straße 5, 2700 Wiener Neustadt, Austria. Electronic address: alessio.elia@medaustron.at. 2. Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Währinger Gürtel 18-20, Medical University of Vienna, Austria; Department of Radiation Oncology, Division Medical Physics, Medical University Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria. 3. EBG MedAustron GmbH, Marie-Curie Straße 5, 2700 Wiener Neustadt, Austria. 4. EBG MedAustron GmbH, Marie-Curie Straße 5, 2700 Wiener Neustadt, Austria; Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Währinger Gürtel 18-20, Medical University of Vienna, Austria; Department of Radiation Oncology, Division Medical Physics, Medical University Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria. 5. EBG MedAustron GmbH, Marie-Curie Straße 5, 2700 Wiener Neustadt, Austria; National Physical Laboratory, Teddington TW 11 0LW, United Kingdom. 6. Université de Lyon, CREATIS; CNRS UMR5220; Inserm U1044; INSA-Lyon; Université Lyon 1; Centre Léon Bérard, France.
Abstract
PURPOSE: To present a reference Monte Carlo (MC) beam model developed in GATE/Geant4 for the MedAustron fixed beam line. The proposed model includes an absolute dose calibration in Dose-Area-Product (DAP) and it has been validated within clinical tolerances for non-isocentric treatments as routinely performed at MedAustron. MATERIAL AND METHODS: The proton beam model was parametrized at the nozzle entrance considering optic and energy properties of the pencil beam. The calibration in terms of absorbed dose to water was performed exploiting the relationship between number of particles and DAP by mean of a recent formalism. Typical longitudinal dose distribution parameters (range, distal penumbra and modulation) and transverse dose distribution parameters (spot sizes, field sizes and lateral penumbra) were evaluated. The model was validated in water, considering regular-shaped dose distribution as well as clinical plans delivered in non-isocentric conditions. RESULTS: Simulated parameters agree with measurements within the clinical requirements at different air gaps. The agreement of distal and longitudinal dose distribution parameters is mostly better than 1 mm. The dose difference in reference conditions and for 3D dose delivery in water is within 0.5% and 1.2%, respectively. Clinical plans were reproduced within 3%. CONCLUSION: A full nozzle beam model for active scanning proton pencil beam is described using GATE/Geant4. Absolute dose calibration based on DAP formalism was implemented. The beam model is fully validated in water over a wide range of clinical scenarios and will be inserted as a reference tool for research and for independent dose calculation in the clinical routine.
PURPOSE: To present a reference Monte Carlo (MC) beam model developed in GATE/Geant4 for the MedAustron fixed beam line. The proposed model includes an absolute dose calibration in Dose-Area-Product (DAP) and it has been validated within clinical tolerances for non-isocentric treatments as routinely performed at MedAustron. MATERIAL AND METHODS: The proton beam model was parametrized at the nozzle entrance considering optic and energy properties of the pencil beam. The calibration in terms of absorbed dose to water was performed exploiting the relationship between number of particles and DAP by mean of a recent formalism. Typical longitudinal dose distribution parameters (range, distal penumbra and modulation) and transverse dose distribution parameters (spot sizes, field sizes and lateral penumbra) were evaluated. The model was validated in water, considering regular-shaped dose distribution as well as clinical plans delivered in non-isocentric conditions. RESULTS: Simulated parameters agree with measurements within the clinical requirements at different air gaps. The agreement of distal and longitudinal dose distribution parameters is mostly better than 1 mm. The dose difference in reference conditions and for 3D dose delivery in water is within 0.5% and 1.2%, respectively. Clinical plans were reproduced within 3%. CONCLUSION: A full nozzle beam model for active scanning proton pencil beam is described using GATE/Geant4. Absolute dose calibration based on DAP formalism was implemented. The beam model is fully validated in water over a wide range of clinical scenarios and will be inserted as a reference tool for research and for independent dose calculation in the clinical routine.
Authors: Adam H Aitkenhead; Peter Sitch; Jenny C Richardson; Carla Winterhalter; Imran Patel; Ranald I Mackay Journal: Br J Radiol Date: 2020-07-29 Impact factor: 3.039
Authors: Andreas Franz Resch; Mansure Schafasand; Niklas Lackner; Tom Niessen; Staffan Beck; Alessio Elia; David Boersma; Loïc Grevillot; Piero Fossati; Lars Glimelius; Markus Stock; Dietmar Georg; Antonio Carlino Journal: Med Phys Date: 2022-04-27 Impact factor: 4.506
Authors: Andreas F Resch; Fatima Padilla Cabal; Milovan Regodic; Wolfgang Lechner; Gerd Heilemann; Peter Kuess; Dietmar Georg; Hugo Palmans Journal: Med Phys Date: 2022-07-14 Impact factor: 4.506