Literature DB >> 32125825

Nanocarriers for the Delivery of Medical, Veterinary, and Agricultural Active Ingredients.

Paul L Chariou, Oscar A Ortega-Rivera, Nicole F Steinmetz.   

Abstract

Nanocarrier-based delivery systems can be used to increase the safety and efficacy of active ingredients in medical, veterinary, or agricultural applications, particularly when such ingredients are unstable, sparingly soluble, or cause off-target effects. In this review, we highlight the diversity of nanocarrier materials and their key advantages compared to free active ingredients. We discuss current trends based on peer-reviewed research articles, patent applications, clinical trials, and the nanocarrier formulations already approved by regulatory bodies. Although most nanocarriers have been engineered to combat cancer, the number of formulations developed for other purposes is growing rapidly, especially those for the treatment of infectious diseases and parasites affecting humans, livestock, and companion animals. The regulation and prohibition of many pesticides have also fueled research to develop targeted pesticide delivery systems based on nanocarriers, which maximize efficacy while minimizing the environmental impact of agrochemicals.

Entities:  

Keywords:  agrochemical delivery; cancer; clinical trials; drug delivery; gene delivery; nanocarrier; nanomedicine; pest management; precision farming; veterinary medicine

Mesh:

Substances:

Year:  2020        PMID: 32125825     DOI: 10.1021/acsnano.0c00173

Source DB:  PubMed          Journal:  ACS Nano        ISSN: 1936-0851            Impact factor:   15.881


  20 in total

Review 1.  Nanoscale covalent organic frameworks as theranostic platforms for oncotherapy: synthesis, functionalization, and applications.

Authors:  Qun Guan; Guang-Bo Wang; Le-Le Zhou; Wen-Yan Li; Yu-Bin Dong
Journal:  Nanoscale Adv       Date:  2020-07-16

Review 2.  Harnessing the Therapeutic Potential of Biomacromolecules through Intracellular Delivery of Nucleic Acids, Peptides, and Proteins.

Authors:  Yu Tian; Matthew V Tirrell; James L LaBelle
Journal:  Adv Healthc Mater       Date:  2022-03-23       Impact factor: 11.092

3.  Effect of a Novel Hybrid Nanocomposite of Cisplatin-Chitosan on Induced Tissue Injury as a Suggested Drug by Reducing Cisplatin Side Effects.

Authors:  Nagi M El-Shafai; Foad Farrag; Mustafa Shukry; Hany Mehany; Mohamed Aboelmaati; Ola Abu-Ali; Dalia Saleh; Mohamed Ramadan; Ibrahim El-Mehasseb
Journal:  Biol Trace Elem Res       Date:  2021-10-31       Impact factor: 4.081

4.  The International Society of RNA Nanotechnology and Nanomedicine (ISRNN): The Present and Future of the Burgeoning Field.

Authors:  Morgan Chandler; Brittany Johnson; Emil Khisamutdinov; Marina A Dobrovolskaia; Joanna Sztuba-Solinska; Aliasger K Salem; Koen Breyne; Roger Chammas; Nils G Walter; Lydia M Contreras; Peixuan Guo; Kirill A Afonin
Journal:  ACS Nano       Date:  2021-10-22       Impact factor: 18.027

Review 5.  The pharmacology of plant virus nanoparticles.

Authors:  Christian Isalomboto Nkanga; Nicole F Steinmetz
Journal:  Virology       Date:  2021-01-28       Impact factor: 3.616

Review 6.  Control of sheep flystrike: what's been tried in the past and where to from here.

Authors:  A C Kotze; P J James
Journal:  Aust Vet J       Date:  2021-11-10       Impact factor: 1.343

Review 7.  Fate of Biodegradable Engineered Nanoparticles Used in Veterinary Medicine as Delivery Systems from a One Health Perspective.

Authors:  Constantin Cerbu; Melanie Kah; Jason C White; Carlos E Astete; Cristina M Sabliov
Journal:  Molecules       Date:  2021-01-20       Impact factor: 4.411

8.  Nano-pesticides: the lunch-box principle-deadly goodies (semio-chemical functionalised nanoparticles that deliver pesticide only to target species).

Authors:  J J Scott-Fordsmand; L F Fraceto; M J B Amorim
Journal:  J Nanobiotechnology       Date:  2022-01-04       Impact factor: 10.435

Review 9.  Combining nanomedicine and immune checkpoint therapy for cancer immunotherapy.

Authors:  Christine E Boone; Lu Wang; Aayushma Gautam; Isabel G Newton; Nicole F Steinmetz
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2021-07-22

10.  Label-free characterization of organic nanocarriers reveals persistent single molecule cores for hydrocarbon sequestration.

Authors:  Terry McAfee; Thomas Ferron; Isvar A Cordova; Phillip D Pickett; Charles L McCormick; Cheng Wang; Brian A Collins
Journal:  Nat Commun       Date:  2021-05-25       Impact factor: 14.919

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