Literature DB >> 32124016

Fertility preservation treatment of gynecological cancer patients in Spain: a national survey (GOFER study).

Mikel Gorostidi1, Blanca Gil-Ibañez2, Sonsoles Alonso3, Antonio Gil-Moreno4,5, Alicia Hernandez6, Aureli Torné7, Ignacio Zapardiel6.   

Abstract

PURPOSE: To analyze the current management and use of fertility preservation (FP) treatments among different gynecologic oncology centers in Spain
METHODS: From March to April 2019, a transversal study was conducted using a national online survey to consultants registered in the section of Gynecologic Oncology of the Spanish Society of Obstetrics and Gynecology. The survey contained 30 questions that assessed the perceptions and attitudes towards fertility-sparing strategies as well as its management in each participating center.
RESULTS: A total of 51 responders from 12 out of 17 geographical regions of Spain answered the survey. According to 35 responders (68.63%), the age limit for offering FP was 40 years. In most of the centers, an ovarian reserve study is carried out prior to a FP procedure (34 responders, 66.67%). In cervical cancer size, limit for offering trachelectomy is 2 cm (40 responders, 78.43%), with LVSI as an exclusion factor for 26 (51%). Twenty-four (48.98%) responders reported that FP only in ovarian cancer stages IA, 12 (24.49%) also in stages IB, and an additional 13 (26.53%) up to stages IC. Most responders perform FP only in the absence of myometrial infiltration (30, 58.82%) in patients with g1-g2 endometrial cancer.
CONCLUSIONS: The performance of professionals at the national level is uneven, demonstrating the need for referral centers to ensure optimal management. International guidelines should be more widely extended throughout Spain to homogenize the treatment of young oncology patients who wish to have children.

Entities:  

Keywords:  Conservative treatment endometrial cancer; Early cervical cancer; Fertility preservation treatments; Gynecological cancer

Mesh:

Year:  2020        PMID: 32124016     DOI: 10.1007/s00404-020-05468-8

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  19 in total

1.  Oncological and pregnancy outcomes after high-dose density neoadjuvant chemotherapy and fertility-sparing surgery in cervical cancer.

Authors:  Helena Robova; Michael J Halaska; Marek Pluta; Petr Skapa; Jan Matecha; Jiri Lisy; Lukas Rob
Journal:  Gynecol Oncol       Date:  2014-08-23       Impact factor: 5.482

2.  Fertility sparing treatment of complex atypical hyperplasia and low grade endometrial cancer using oral progestin.

Authors:  Andrea N Simpson; Tomer Feigenberg; Blaise A Clarke; Lilian T Gien; Nadia Ismiil; Stephane Laframboise; Christine Massey; Sarah E Ferguson
Journal:  Gynecol Oncol       Date:  2014-02-19       Impact factor: 5.482

3.  Outcomes of patients undergoing radical hysterectomy for cervical cancer of high-risk histological subtypes.

Authors:  Sonika Agarwal; Kathleen M Schmeler; Pedro T Ramirez; Charlotte C Sun; Alpa Nick; Ricardo Dos Reis; Jubilee Brown; Michael Frumovitz
Journal:  Int J Gynecol Cancer       Date:  2011-01       Impact factor: 3.437

4.  Vaginal Radical Trachelectomy for Early-Stage Cervical Cancer: Increased Recurrence Risk for Adenocarcinoma.

Authors:  Petra L M Zusterzeel; Fraukje J M Pol; Maaike van Ham; Ronald P Zweemer; Ruud L M Bekkers; Leon F A G Massuger; René H M Verheijen
Journal:  Int J Gynecol Cancer       Date:  2016-09       Impact factor: 3.437

5.  The European Society of Gynaecological Oncology/European Society for Radiotherapy and Oncology/European Society of Pathology Guidelines for the Management of Patients With Cervical Cancer.

Authors:  David Cibula; Richard Pötter; François Planchamp; Elisabeth Avall-Lundqvist; Daniela Fischerova; Christine Haie Meder; Christhardt Köhler; Fabio Landoni; Sigurd Lax; Jacob Christian Lindegaard; Umesh Mahantshetty; Patrice Mathevet; W Glenn McCluggage; Mary McCormack; Raj Naik; Remi Nout; Sandro Pignata; Jordi Ponce; Denis Querleu; Francesco Raspagliesi; Alexandros Rodolakis; Karl Tamussino; Pauline Wimberger; Maria Rosaria Raspollini
Journal:  Int J Gynecol Cancer       Date:  2018-05       Impact factor: 3.437

6.  Early adenocarcinoma of the cervix: is radical vaginal trachelectomy safe?

Authors:  L Helpman; D Grisaru; A Covens
Journal:  Gynecol Oncol       Date:  2011-07-20       Impact factor: 5.482

Review 7.  Conservative treatment of early stage ovarian cancer: oncological and fertility outcomes.

Authors:  I Zapardiel; M D Diestro; G Aletti
Journal:  Eur J Surg Oncol       Date:  2013-12-13       Impact factor: 4.424

Review 8.  Oncological outcomes after fertility-sparing surgery for cervical cancer: a systematic review.

Authors:  Enrica Bentivegna; Sebastien Gouy; Amandine Maulard; Cyrus Chargari; Alexandra Leary; Philippe Morice
Journal:  Lancet Oncol       Date:  2016-06       Impact factor: 41.316

9.  Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer.

Authors:  Pedro T Ramirez; Michael Frumovitz; Rene Pareja; Aldo Lopez; Marcelo Vieira; Reitan Ribeiro; Alessandro Buda; Xiaojian Yan; Yao Shuzhong; Naven Chetty; David Isla; Mariano Tamura; Tao Zhu; Kristy P Robledo; Val Gebski; Rebecca Asher; Vanessa Behan; James L Nicklin; Robert L Coleman; Andreas Obermair
Journal:  N Engl J Med       Date:  2018-10-31       Impact factor: 91.245

Review 10.  Fertility-sparing management in cervical cancer: balancing oncologic outcomes with reproductive success.

Authors:  Karla Willows; Genevieve Lennox; Allan Covens
Journal:  Gynecol Oncol Res Pract       Date:  2016-10-21
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  2 in total

1.  Tumor Size and Oncological Outcomes in Patients with Early Cervical Cancer Treated by Fertility Preservation Surgery: A Multicenter Retrospective Cohort Study.

Authors:  Blanca Gil-Ibañez; Antonio Gil-Moreno; Aureli Torné; Angel Martín Jimenez; Mikel Gorostidi; Ignacio Zapardiel; Alvaro Tejerizo Garcia; Berta Diaz-Feijoo
Journal:  Cancers (Basel)       Date:  2022-04-23       Impact factor: 6.575

2.  Fertility-Sparing Surgery versus Radical Hysterectomy in Early Cervical Cancer: A Propensity Score Matching Analysis and Noninferiority Study.

Authors:  Antoni Llueca; Maria Victoria Ibañez; Aureli Torne; Antonio Gil-Moreno; Angel Martin-Jimenez; Berta Diaz-Feijoo; Anna Serra; Maria Teresa Climent; Blanca Gil-Ibañez
Journal:  J Pers Med       Date:  2022-06-30
  2 in total

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