Literature DB >> 32119070

A Path Recorder Algorithm for Multiple Longest Common Subsequences (MLCS) Problems.

Shiwei Wei1,2, Yuping Wang1, Yuanchao Yang1, Sen Liu1.   

Abstract

MOTIVATION: Searching the Longest Common Subsequences of many sequences is called a Multiple Longest Common Subsequence (MLCS) problem which is a very fundamental and challenging problem in many fields of data mining. The existing algorithms cannot not applicable to problems with long and large-scale sequences due to their huge time and space consumption. To efficiently handle large-scale MLCS problems, a Path Recorder Directed Acyclic Graph (PRDAG) model and a novel Path Recorder Algorithm (PRA) are proposed.
RESULTS: In PRDAG, we transform the MLCS problem into searching the longest path from the Directed Acyclic Graph (DAG), where each longest path in DAG corresponds to an MLCS. To tackle the problem efficiently, we eliminate all redundant and repeated nodes during the construction of DAG, and for each node, we only maintain the longest paths from the source node to it but ignore all non-longest pathes. As a result, the size of the DAG becomes very small, and the memory space and search time will be greatly saved. Empirical experiments have been performed on a standard benchmark set of both DNA sequences and protein sequences. The experimental results demonstrate that our model and algorithm outperform the related leading algorithms, especially for large-scale MLCS problems.
© The Author(s) (2020). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Year:  2020        PMID: 32119070     DOI: 10.1093/bioinformatics/btaa134

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  1 in total

1.  A fast and efficient path elimination algorithm for large-scale multiple common longest sequence problems.

Authors:  Changyong Yu; Pengxi Lin; Yuhai Zhao; Tianmei Ren; Guoren Wang
Journal:  BMC Bioinformatics       Date:  2022-09-07       Impact factor: 3.307

  1 in total

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