Literature DB >> 32118572

Factors Associated with Differential Readmission Diagnoses Following Acute Exacerbations of Chronic Obstructive Pulmonary Disease.

Russell G Buhr1,2,3, Nicholas J Jackson4, Steven M Dubinett1,3, Gerald F Kominski2,5, Carol M Mangione2,6, Michael K Ong2,3,6.   

Abstract

BACKGROUND: Readmissions after exacerbations of chronic obstructive pulmonary disease (COPD) are penalized under the Hospital Readmissions Reduction Program (HRRP). Understanding attributable diagnoses at readmission would improve readmission reduction strategies.
OBJECTIVES: Determine factors that portend 30-day readmissions attributable to COPD versus non-COPD diagnoses among patients discharged following COPD exacerbations. DESIGN, SETTING, AND PARTICIPANTS: We analyzed COPD discharges in the Nationwide Readmissions Database from 2010 to 2016 using inclusion and readmission definitions in HRRP. MAIN OUTCOMES AND MEASURES: We evaluated readmission odds for COPD versus non-COPD returns using a multilevel, multinomial logistic regression model. Patient-level covariates included age, sex, community characteristics, payer, discharge disposition, and Elixhauser Comorbidity Index. Hospital-level covariates included hospital ownership, teaching status, volume of annual discharges, and proportion of Medicaid patients.
RESULTS: Of 1,622,983 (a weighted effective sample of 3,743,164) eligible COPD hospitalizations, 17.25% were readmitted within 30 days (7.69% for COPD and 9.56% for other diagnoses). Sepsis, heart failure, and respiratory infections were the most common non-COPD return diagnoses. Patients readmitted for COPD were younger with fewer comorbidities than patients readmitted for non-COPD. COPD returns were more prevalent the first two days after discharge than non-COPD returns. Comorbidity was a stronger driver for non-COPD (odds ratio [OR] 1.19) than COPD (OR 1.04) readmissions.
CONCLUSION: Thirty-day readmissions following COPD exacerbations are common, and 55% of them are attributable to non-COPD diagnoses at the time of return. Higher burden of comorbidity is observed among non-COPD than COPD rehospitalizations. Readmission reduction efforts should focus intensively on factors beyond COPD disease management to reduce readmissions considerably by aggressively attempting to mitigate comorbid conditions.

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Year:  2020        PMID: 32118572      PMCID: PMC7153488          DOI: 10.12788/jhm.3367

Source DB:  PubMed          Journal:  J Hosp Med        ISSN: 1553-5592            Impact factor:   2.960


  36 in total

1.  The validity of International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis codes for identifying patients hospitalized for COPD exacerbations.

Authors:  Brian D Stein; Adriana Bautista; Glen T Schumock; Todd A Lee; Jeffery T Charbeneau; Diane S Lauderdale; Edward T Naureckas; David O Meltzer; Jerry A Krishnan
Journal:  Chest       Date:  2011-07-14       Impact factor: 9.410

2.  Moving prediction of exacerbation in chronic obstructive pulmonary disease for patients in telecare.

Authors:  Morten H Jensen; Simon L Cichosz; Birthe Dinesen; Ole K Hejlesen
Journal:  J Telemed Telecare       Date:  2012-01-20       Impact factor: 6.184

3.  Adverse consequences of glucocorticoid medication: psychological, cognitive, and behavioral effects.

Authors:  Lewis L Judd; Pamela J Schettler; E Sherwood Brown; Owen M Wolkowitz; Esther M Sternberg; Bruce G Bender; Karen Bulloch; John A Cidlowski; E Ronald de Kloet; Laurence Fardet; Marian Joëls; Donald Y M Leung; Bruce S McEwen; Benno Roozendaal; Elisabeth F C Van Rossum; Junyoung Ahn; David W Brown; Aaron Plitt; Gagandeep Singh
Journal:  Am J Psychiatry       Date:  2014-10       Impact factor: 18.112

4.  Understanding why patients with COPD get readmitted: a large national study to delineate the Medicare population for the readmissions penalty expansion.

Authors:  Tina Shah; Matthew M Churpek; Marcelo Coca Perraillon; R Tamara Konetzka
Journal:  Chest       Date:  2015-05       Impact factor: 9.410

5.  Chronic obstructive pulmonary disease is associated with increased recurrent peptic ulcer bleeding risk.

Authors:  Kuang-Wei Huang; Yi-Chun Kuan; Nai-Fang Chi; Yao-Hsien Huang; Jiing-Chyuan Luo; Li-Nien Chien
Journal:  Eur J Intern Med       Date:  2016-10-07       Impact factor: 4.487

Review 6.  Insights about the economic impact of chronic obstructive pulmonary disease readmissions post implementation of the hospital readmission reduction program.

Authors:  Valerie G Press; R Tamara Konetzka; Steven R White
Journal:  Curr Opin Pulm Med       Date:  2018-03       Impact factor: 3.155

7.  Impact of Comorbidities Among Medicaid Enrollees With Chronic Obstructive Pulmonary Disease, United States, 2009.

Authors:  Gloria Westney; Marilyn G Foreman; Junjun Xu; Marshaleen Henriques King; Eric Flenaugh; George Rust
Journal:  Prev Chronic Dis       Date:  2017-04-13       Impact factor: 2.830

Review 8.  Self management for patients with chronic obstructive pulmonary disease.

Authors:  Marlies Zwerink; Marjolein Brusse-Keizer; Paul D L P M van der Valk; Gerhard A Zielhuis; Evelyn M Monninkhof; Job van der Palen; Peter A Frith; Tanja Effing
Journal:  Cochrane Database Syst Rev       Date:  2014-03-19

9.  Early Hospital Readmissions after an Acute Exacerbation of Chronic Obstructive Pulmonary Disease in the Nationwide Readmissions Database.

Authors:  David M Jacobs; Katia Noyes; Jiwei Zhao; Walter Gibson; Timothy F Murphy; Sanjay Sethi; Heather M Ochs-Balcom
Journal:  Ann Am Thorac Soc       Date:  2018-07

10.  Reducing Chronic Obstructive Pulmonary Disease Hospital Readmissions. An Official American Thoracic Society Workshop Report.

Authors:  Valerie G Press; David H Au; Jean Bourbeau; Mark T Dransfield; Andrea S Gershon; Jerry A Krishnan; Richard A Mularski; Frank C Sciurba; Jamie Sullivan; Laura C Feemster
Journal:  Ann Am Thorac Soc       Date:  2019-02
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  5 in total

1.  The Hospital Readmissions Reduction Program and COPD: More Answers, More Questions.

Authors:  Valerie G Press; Brian J Miller
Journal:  J Hosp Med       Date:  2020-02-11       Impact factor: 2.960

2.  Effects of Obstructive Sleep Apnea and Obesity on 30-Day Readmissions in Patients with Chronic Obstructive Pulmonary Disease: A Cross-Sectional Mediation Analysis.

Authors:  Jessica E Channick; Nicholas J Jackson; Michelle R Zeidler; Russell G Buhr
Journal:  Ann Am Thorac Soc       Date:  2022-03

3.  30-day Readmission After an Acute Exacerbation of Chronic Obstructive Pulmonary Disease is Associated with Cardiovascular Comorbidity.

Authors:  Aylin Ozgen Alpaydin; Saliha Selin Ozuygur; Ceyda Sahan; Kemal Can Tertemiz; Richard Russell
Journal:  Turk Thorac J       Date:  2021-09

4.  Machine-learning prediction of unplanned 30-day rehospitalization using the French hospital medico-administrative database.

Authors:  Franck Jaotombo; Vanessa Pauly; Pascal Auquier; Veronica Orleans; Mohamed Boucekine; Guillaume Fond; Badih Ghattas; Laurent Boyer
Journal:  Medicine (Baltimore)       Date:  2020-12-04       Impact factor: 1.817

5.  Readmissions Reduction Program: Mortality and Readmissions for Chronic Obstructive Pulmonary Disease.

Authors:  Daniel A Puebla Neira; En Shuo Hsu; Yong-Fang Kuo; Kenneth J Ottenbacher; Gulshan Sharma
Journal:  Am J Respir Crit Care Med       Date:  2021-02-15       Impact factor: 21.405

  5 in total

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