Literature DB >> 32114568

Effects of Grape Seed Proanthocyanidin Extract on Obesity.

Miao Liu1, Peng Yun2, Ying Hu1, Jiao Yang1, Rim Bahadur Khadka3, Xiaochun Peng4.   

Abstract

Obesity is a chronic metabolic disease resulting from excessive fat accumulation and/or abnormal distribution caused by multiple factors. As a major component of metabolic syndrome, obesity is closely related to many diseases such as type 2 diabetes mellitus, hyperlipidemia, hypertension, coronary heart disease, stroke and cancer. Hence, the problem of obesity cannot be ignored, and recent studies have shown that grape seed proanthocyanidin extract (GSPE) has an antiobesity effect. This paper systematically reviews the research progress and potential mechanism of GSPE emphasizing on obesity prevention and treatment.
© 2020 The Author(s) Published by S. Karger AG, Basel.

Entities:  

Keywords:  Grape seed proanthocyanidin extract; Mechanism; Obesity

Year:  2020        PMID： 32114568      PMCID： PMC7250358          DOI： 10.1159/000502235

Source DB:  PubMed          Journal:  Obes Facts        ISSN： 1662-4025            Impact factor:   3.942


  98 in total

1.  Stage-specific effects of a thiazolidinedione on proliferation, differentiation and PPARgamma mRNA expression in 3T3-L1 adipocytes.

Authors:  T Takamura; E Nohara; Y Nagai; K Kobayashi
Journal:  Eur J Pharmacol       Date:  2001-06-22       Impact factor: 4.432

2.  Role of GSPE in improving early cerebral vascular damage by inhibition of Profilin-1 expression in a ouabain-induced hypertension model.

Authors:  J-P Hao; H Shi; J Zhang; C-M Zhang; Y-M Feng; L-Y Qie; M Dong; X Ji
Journal:  Eur Rev Med Pharmacol Sci       Date:  2018-10       Impact factor: 3.507

3.  Grape seed proanthocyanidin extract inhibits interleukin-17-induced interleukin-6 production via MAPK pathway in human pulmonary epithelial cells.

Authors:  Hyeongseok Kim; Jin Young Kim; Hong Suk Song; Keon Uk Park; Kyo-Chul Mun; Eunyoung Ha
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2011-04-12       Impact factor: 3.000

Review 4.  An Overview of Links Between Obesity and Mental Health.

Authors:  Christian Avila; Alison C Holloway; Margaret K Hahn; Katherine M Morrison; Maria Restivo; Rebecca Anglin; Valerie H Taylor
Journal:  Curr Obes Rep       Date:  2015-09

5.  Dietary grape seed procyanidin extract protects against lead-induced heart injury in rats involving endoplasmic reticulum stress inhibition and AKT activation.

Authors:  Daqian Yang; Siyu Li; Li Gao; Zhanjun Lv; Qizheng Bing; Qingjie Lv; Xiaoyan Zheng; Ruobing Li; Zhigang Zhang
Journal:  J Nutr Biochem       Date:  2018-08-14       Impact factor: 6.048

Review 6.  MALDI-TOF MS analysis of plant proanthocyanidins.

Authors:  María Monagas; Jesús Eduardo Quintanilla-López; Carmen Gómez-Cordovés; Begoña Bartolomé; Rosa Lebrón-Aguilar
Journal:  J Pharm Biomed Anal       Date:  2009-04-07       Impact factor: 3.935

7.  Intestinal gluconeogenesis is crucial to maintain a physiological fasting glycemia in the absence of hepatic glucose production in mice.

Authors:  Armelle Penhoat; Laetitia Fayard; Anne Stefanutti; Gilles Mithieux; Fabienne Rajas
Journal:  Metabolism       Date:  2013-10-14       Impact factor: 8.694

8.  Grape seed proanthocyanidin extract protects human lens epithelial cells from oxidative stress via reducing NF-кB and MAPK protein expression.

Authors:  Zhiyan Jia; Zhen Song; Yuhui Zhao; Xiurong Wang; Ping Liu
Journal:  Mol Vis       Date:  2011-01-20       Impact factor: 2.367

Review 9.  Obesity: Risk factors, complications, and strategies for sustainable long-term weight management.

Authors:  Sharon M Fruh
Journal:  J Am Assoc Nurse Pract       Date:  2017-10       Impact factor: 1.495

Review 10.  Energy balance, body composition, sedentariness and appetite regulation: pathways to obesity.

Authors:  Mark Hopkins; John E Blundell
Journal:  Clin Sci (Lond)       Date:  2016-09-01       Impact factor: 6.124
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  5 in total

1.  Effectiveness of Proanthocyanidin plus Trimetazidine in the Treatment of Non-Small-Cell Lung Cancer with Radiation Heart Injury.

Authors:  Hang Yin; Yue Zhao; Yucui Sun; Jia Liu; Yingjun Han; Zhentao Dai
Journal:  Evid Based Complement Alternat Med       Date:  2022-06-03       Impact factor: 2.650

2.  Optimization of the Extraction of Proanthocyanidins from Grape Seeds Using Ultrasonication-Assisted Aqueous Ethanol and Evaluation of Anti-Steatosis Activity In Vitro.

Authors:  Wasitha P D W Thilakarathna; H P Vasantha Rupasinghe
Journal:  Molecules       Date:  2022-02-17       Impact factor: 4.411

3.  Dietary Grape Seed Proanthocyanidin Alleviates the Liver Injury Induced by Long-Term High-Fat Diets in Sprague Dawley Rats.

Authors:  Hao Yang Sun; Ai Xin Gu; Bi Ying Huang; Tong Zhang; Jian Ping Li; An Shan Shan
Journal:  Front Vet Sci       Date:  2022-08-03

4.  Grape-Seed Proanthocyanidin Extract Reverts Obesity-Related Metabolic Derangements in Aged Female Rats.

Authors:  Marta Sierra-Cruz; Alba Miguéns-Gómez; Carme Grau-Bové; Esther Rodríguez-Gallego; Mayte Blay; Montserrat Pinent; Anna Ardévol; Ximena Terra; Raúl Beltrán-Debón
Journal:  Nutrients       Date:  2021-06-16       Impact factor: 5.717

5.  Grape seed proanthocyanidin extract induces apoptosis of HL-60/ADR cells via the Bax/Bcl-2 caspase-3/9 signaling pathway.

Authors:  Ka-Na Lin; Wei Zhao; Shi-Ying Huang; Hao Li
Journal:  Transl Cancer Res       Date:  2021-09       Impact factor: 1.241
  5 in total

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