Literature DB >> 32111795

Risk Factors for Postoperative Anastomosis Leak After Esophagectomy for Esophageal Cancer.

Toru Aoyama1, Yosuke Atsumi2, Kentaro Hara2, Hiroshi Tamagawa2, Ayako Tamagawa2, Keisuke Komori2, Itaru Hashimoto2, Yukio Maezawa2, Keisuke Kazama2, Kazuki Kano2, Masaaki Murakawa2, Masakatsu Numata2, Takashi Oshima2, Norio Yukawa2, Munetaka Masuda2, Yasushi Rino2.   

Abstract

BACKGROUND/AIM: The present study aimed to identify risk factors for anastomosis leak (AL) after esophagectomy for esophageal cancer. PATIENTS AND METHODS: One-hundred twenty-two patients who underwent esophagectomy for esophageal cancer between 2008 and 2018 were included. The rate of AL was measured based on the definition of leak as adapted from the Surgical Infection Study Group. To identify the risk factors for AL, logistic regression analysis was used.
RESULTS: AL was found in 44 of the 122 patients (36.1%). Among the factors examined, the lymph node dissection status (p=0.007) and preoperative serum albumin level (p=0.022) were significant independent risk factors for AL. The incidence of AL was 26.7% (20 of 75) among patients who received 2-field lymph node dissection and 51.1% (24 of 47) among those who received 3-field lymph node dissection. The incidence of AL was 29.9% (23 of 77) in the preoperative serum albumin levels ≥4.0 g/dl group and 46.7% (21 of 45) in the serum albumin levels <4.0 g/dl group.
CONCLUSION: Lymph node dissection status and preoperative serum albumin levels were risk factors for AL in patients who received esophagectomy for esophageal cancer. Copyright
© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Esophageal cancer; anastomosis leak; risk factor

Mesh:

Year:  2020        PMID: 32111795      PMCID: PMC7157851          DOI: 10.21873/invivo.11849

Source DB:  PubMed          Journal:  In Vivo        ISSN: 0258-851X            Impact factor:   2.155


  27 in total

Review 1.  The volume-outcome relation in the surgical treatment of esophageal cancer: a systematic review and meta-analysis.

Authors:  Michel W J M Wouters; Gea A Gooiker; Johanna W van Sandick; Rob A E M Tollenaar
Journal:  Cancer       Date:  2011-08-25       Impact factor: 6.860

2.  Immediate Postoperative Oral Nutrition Following Esophagectomy: A Multicenter Clinical Trial.

Authors:  Teus J Weijs; Gijs H K Berkelmans; Grard A P Nieuwenhuijzen; Annemarie C P Dolmans; Ewout A Kouwenhoven; Camiel Rosman; Jelle P Ruurda; Frans van Workum; Marc J van Det; Luis C Silva Corten; Richard van Hillegersberg; Misha D P Luyer
Journal:  Ann Thorac Surg       Date:  2016-06-17       Impact factor: 4.330

3.  The Impact of Severe Anastomotic Leak on Long-term Survival and Cancer Recurrence After Surgical Resection for Esophageal Malignancy.

Authors:  Sheraz Markar; Caroline Gronnier; Alain Duhamel; Jean-Yves Mabrut; Jean-Pierre Bail; Nicolas Carrere; Jérémie H Lefevre; Cécile Brigand; Jean-Christophe Vaillant; Mustapha Adham; Simon Msika; Nicolas Demartines; Issam El Nakadi; Bernard Meunier; Denis Collet; Christophe Mariette
Journal:  Ann Surg       Date:  2015-12       Impact factor: 12.969

4.  Regular Alcohol Consumption Is Associated With Impaired Atrial Mechanical Function in the Atrial Fibrillation Population: A Cross-Sectional MRI-Based Study.

Authors:  Aleksandr Voskoboinik; Benedict T Costello; Elana Kalman; Sandeep Prabhu; Hariharan Sugumar; Geoff Wong; Chrishan Nalliah; Liang-Han Ling; Alex McLellan; Thushan Hettige; Fabian Springer; Andre La Gerche; Jonathan M Kalman; Andrew J Taylor; Peter M Kistler
Journal:  JACC Clin Electrophysiol       Date:  2018-09-26

5.  Impact of neoadjuvant chemoradiotherapy on postoperative outcomes after esophageal cancer resection: results of a European multicenter study.

Authors:  Caroline Gronnier; Boris Tréchot; Alain Duhamel; Jean-Yves Mabrut; Jean-Pierre Bail; Nicolas Carrere; Jérémie H Lefevre; Cécile Brigand; Jean-Christophe Vaillant; Mustapha Adham; Simon Msika; Nicolas Demartines; Issam El Nakadi; Guillaume Piessen; Bernard Meunier; Denis Collet; Christophe Mariette; Guillaume Luc; Magalie Cabau; Jacques Jougon; Bogdan Badic; Patrick Lozach; Serge Cappeliez; Gil Lebreton; Arnaud Alves; Renaud Flamein; Denis Pezet; Federica Pipitone; Bogdan Stan Iuga; Nicolas Contival; Eric Pappalardo; Styliani Mantziari; Flora Hec; Marguerite Vanderbeken; Williams Tessier; Nicolas Briez; Fabien Fredon; Alain Gainant; Muriel Mathonnet; Jean-Marc Bigourdan; Salim Mezoughi; Christian Ducerf; Jacques Baulieux; Arnaud Pasquer; Oussama Baraket; Gilles Poncet; Delphine Vaudoyer; Jourdan Enfer; Laurent Villeneuve; Olivier Glehen; Thibault Coste; Jean Michel Fabre; Frédéric Marchal; Romain Frisoni; Ahmet Ayav; Laurent Brunaud; Laurent Bresler; Charlotte Cohen; Olivier Aze; Nicolas Venissac; Daniel Pop; Jérôme Mouroux; Ion Donici; Michel Prudhomme; Emanuele Felli; Stéphanie Lisunfui; Marie Seman; Gaelle Godiris Petit; Mehdi Karoui; Christophe Tresallet; Fabrice Ménégaux; Laurent Hannoun; Brice Malgras; Denis Lantuas; Karine Pautrat; Marc Pocard; Patrice Valleur
Journal:  Ann Surg       Date:  2014-11       Impact factor: 12.969

Review 6.  Three-field vs two-field lymph node dissection for esophageal cancer: a meta-analysis.

Authors:  Guo-Wei Ma; Dong-Rong Situ; Qi-Long Ma; Hao Long; Lan-Jun Zhang; Peng Lin; Tie-Hua Rong
Journal:  World J Gastroenterol       Date:  2014-12-21       Impact factor: 5.742

7.  Global cancer statistics, 2012.

Authors:  Lindsey A Torre; Freddie Bray; Rebecca L Siegel; Jacques Ferlay; Joannie Lortet-Tieulent; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2015-02-04       Impact factor: 508.702

8.  Short and long-term outcomes after esophagectomy for cancer in elderly patients.

Authors:  Luis F Tapias; Ashok Muniappan; Cameron D Wright; Henning A Gaissert; John C Wain; Christopher R Morse; Dean M Donahue; Douglas J Mathisen; Michael Lanuti
Journal:  Ann Thorac Surg       Date:  2013-03-07       Impact factor: 4.330

9.  Fluid management and postoperative respiratory disturbances in patients with transthoracic esophagectomy for carcinoma.

Authors:  Takashi Kita; Tadanori Mammoto; Yoshihiko Kishi
Journal:  J Clin Anesth       Date:  2002-06       Impact factor: 9.452

Review 10.  Technical factors that affect anastomotic integrity following esophagectomy: systematic review and meta-analysis.

Authors:  Sheraz R Markar; Shobhit Arya; Alan Karthikesalingam; George B Hanna
Journal:  Ann Surg Oncol       Date:  2013-08-14       Impact factor: 5.344

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