Literature DB >> 32110893

The Future of Origin of Life Research: Bridging Decades-Old Divisions.

Martina Preiner1, Silke Asche2, Sidney Becker3, Holly C Betts4, Adrien Boniface5, Eloi Camprubi6, Kuhan Chandru7,8, Valentina Erastova9, Sriram G Garg1, Nozair Khawaja10, Gladys Kostyrka11, Rainer Machné12,13, Giacomo Moggioli14, Kamila B Muchowska15, Sinje Neukirchen16, Benedikt Peter17, Edith Pichlhöfer16, Ádám Radványi18,19, Daniele Rossetto20, Annalena Salditt21, Nicolas M Schmelling12,22, Filipa L Sousa16, Fernando D K Tria1, Dániel Vörös18,19, Joana C Xavier1.   

Abstract

Research on the origin of life is highly heterogeneous. After a peculiar historical development, it still includes strongly opposed views which potentially hinder progress. In the 1st Interdisciplinary Origin of Life Meeting, early-career researchers gathered to explore the commonalities between theories and approaches, critical divergence points, and expectations for the future. We find that even though classical approaches and theories-e.g. bottom-up and top-down, RNA world vs. metabolism-first-have been prevalent in origin of life research, they are ceasing to be mutually exclusive and they can and should feed integrating approaches. Here we focus on pressing questions and recent developments that bridge the classical disciplines and approaches, and highlight expectations for future endeavours in origin of life research.

Entities:  

Keywords:  LUCA; abiogenesis; bottom-up; early life; emergence; origins of life; prebiotic chemistry; top-down

Year:  2020        PMID: 32110893     DOI: 10.3390/life10030020

Source DB:  PubMed          Journal:  Life (Basel)        ISSN: 2075-1729


  8 in total

1.  Searching for Life, Mindful of Lyfe's Possibilities.

Authors:  Michael L Wong; Stuart Bartlett; Sihe Chen; Louisa Tierney
Journal:  Life (Basel)       Date:  2022-05-25

Review 2.  The Legend of ATP: From Origin of Life to Precision Medicine.

Authors:  Xin-Yi Chu; Yuan-Yuan Xu; Xin-Yu Tong; Gang Wang; Hong-Yu Zhang
Journal:  Metabolites       Date:  2022-05-20

3.  Helicase-like functions in phosphate loop containing beta-alpha polypeptides.

Authors:  Pratik Vyas; Olena Trofimyuk; Liam M Longo; Fanindra Kumar Deshmukh; Michal Sharon; Dan S Tawfik
Journal:  Proc Natl Acad Sci U S A       Date:  2021-04-20       Impact factor: 11.205

4.  Inner Workings: Making headway with the mysteries of life's origins.

Authors:  Adam Mann
Journal:  Proc Natl Acad Sci U S A       Date:  2021-04-20       Impact factor: 11.205

Review 5.  Revisiting the Extinction of the RNA World.

Authors:  Anthony C Forster
Journal:  Biochemistry       Date:  2022-04-07       Impact factor: 3.321

6.  A robotic prebiotic chemist probes long term reactions of complexifying mixtures.

Authors:  Silke Asche; Geoffrey J T Cooper; Graham Keenan; Cole Mathis; Leroy Cronin
Journal:  Nat Commun       Date:  2021-06-10       Impact factor: 14.919

7.  A Constructive Way to Think about Different Hydrothermal Environments for the Origins of Life.

Authors:  Arthur Omran; Matthew Pasek
Journal:  Life (Basel)       Date:  2020-04-09

Review 8.  Femtoplankton: What's New?

Authors:  Jonathan Colombet; Maxime Fuster; Hermine Billard; Télesphore Sime-Ngando
Journal:  Viruses       Date:  2020-08-12       Impact factor: 5.048

  8 in total

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