Literature DB >> 32109293

Frequency and Predictors of Tenofovir-diphosphate Detection Among Young Kenyan Women in a Real-world Pre-exposure Prophylaxis Implementation Program.

Jillian Pintye1,2, John Kinuthia1,3, Felix Abuna3, Kenneth Mugwanya1, Harison Lagat3, Julia C Dettinger1, Daniel Odinga3, Joseph Sila3, Peter L Anderson4, Grace John-Stewart1,5,6,7, Jared M Baeten1,5,6.   

Abstract

In a pre-exposure prophylaxis program for Kenyan women, we detected tenofovir-diphosphate in 61% (125/201) of randomly selected dried blood spots collected at the first follow-up visit. Tenofovir-diphosphate was detected more frequently among women who had partners living with human immunodeficiency virus, who were not pregnant, and who were ≥24 years.
© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  HIV/AIDS; adherence; pre-exposure prophylaxis; women

Year:  2020        PMID： 32109293      PMCID： PMC7713682          DOI： 10.1093/cid/ciaa181

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  9 in total

1.  "I Did Not Want to Give Birth to a Child Who has HIV": Experiences Using PrEP During Pregnancy Among HIV-Uninfected Kenyan Women in HIV-Serodiscordant Couples.

Authors:  Jillian Pintye; Kristin M Beima-Sofie; Grace Kimemia; Kenneth Ngure; Susan Brown Trinidad; Renee A Heffron; Jared M Baeten; Josephine Odoyo; Nelly Mugo; Elizabeth A Bukusi; Maureen C Kelley; Grace C John-Stewart
Journal:  J Acquir Immune Defic Syndr       Date:  2017-11-01       Impact factor: 3.731

2.  Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study.

Authors:  Robert M Grant; Peter L Anderson; Vanessa McMahan; Albert Liu; K Rivet Amico; Megha Mehrotra; Sybil Hosek; Carlos Mosquera; Martin Casapia; Orlando Montoya; Susan Buchbinder; Valdilea G Veloso; Kenneth Mayer; Suwat Chariyalertsak; Linda-Gail Bekker; Esper G Kallas; Mauro Schechter; Juan Guanira; Lane Bushman; David N Burns; James F Rooney; David V Glidden
Journal:  Lancet Infect Dis       Date:  2014-07-22       Impact factor: 25.071

3.  Strong Correlation Between Concentrations of Tenofovir (TFV) Emtricitabine (FTC) in Hair and TFV Diphosphate and FTC Triphosphate in Dried Blood Spots in the iPrEx Open Label Extension: Implications for Pre-exposure Prophylaxis Adherence Monitoring.

Authors:  Monica Gandhi; David V Glidden; Albert Liu; Peter L Anderson; Howard Horng; Patricia Defechereux; Juan V Guanira; Beatriz Grinsztejn; Suwat Chariyalertsak; Linda-Gail Bekker; Robert M Grant
Journal:  J Infect Dis       Date:  2015-04-20       Impact factor: 5.226

4.  Intracellular Tenofovir-Diphosphate and Emtricitabine-Triphosphate in Dried Blood Spots following Directly Observed Therapy.

Authors:  Peter L Anderson; Albert Y Liu; Jose R Castillo-Mancilla; Edward M Gardner; Sharon M Seifert; Cricket McHugh; Theresa Wagner; Kayla Campbell; Mary Morrow; Mustafa Ibrahim; Susan Buchbinder; Lane R Bushman; Jennifer J Kiser; Samantha MaWhinney
Journal:  Antimicrob Agents Chemother       Date:  2017-12-21       Impact factor: 5.191

5.  Tenofovir and tenofovir-diphosphate concentrations during pregnancy among HIV-uninfected women using oral preexposure prophylaxis.

Authors:  Maria Pyra; Peter L Anderson; Craig W Hendrix; Renee Heffron; Kenneth Mugwanya; Jessica E Haberer; Katherine K Thomas; Connie Celum; Deborah Donnell; Mark A Marzinke; Elizabeth A Bukusi; Nelly R Mugo; Stephen Asiimwe; Elly Katabira; Jared M Baeten
Journal:  AIDS       Date:  2018-08-24       Impact factor: 4.177

6.  Application of an intracellular assay for determination of tenofovir-diphosphate and emtricitabine-triphosphate from erythrocytes using dried blood spots.

Authors:  Jia-Hua Zheng; Caitlin Rower; Kevin McAllister; Jose Castillo-Mancilla; Brandon Klein; Amie Meditz; L Anthony Guida; Jennifer J Kiser; Lane R Bushman; Peter L Anderson
Journal:  J Pharm Biomed Anal       Date:  2016-01-21       Impact factor: 3.935

7.  Pre-exposure prophylaxis uptake and early continuation among pregnant and post-partum women within maternal and child health clinics in Kenya: results from an implementation programme.

Authors:  John Kinuthia; Jillian Pintye; Felix Abuna; Kenneth K Mugwanya; Harison Lagat; Dickens Onyango; Emily Begnel; Julia Dettinger; Jared M Baeten; Grace John-Stewart
Journal:  Lancet HIV       Date:  2019-12-05       Impact factor: 12.767

Review 8.  HIV pre-exposure prophylaxis for adolescent girls and young women in Africa: from efficacy trials to delivery.

Authors:  Connie L Celum; Sinead Delany-Moretlwe; Jared M Baeten; Ariane van der Straten; Sybil Hosek; Elizabeth A Bukusi; Margaret McConnell; Ruanne V Barnabas; Linda-Gail Bekker
Journal:  J Int AIDS Soc       Date:  2019-07       Impact factor: 5.396

9.  Integrating preexposure prophylaxis delivery in routine family planning clinics: A feasibility programmatic evaluation in Kenya.

Authors:  Kenneth K Mugwanya; Jillian Pintye; John Kinuthia; Felix Abuna; Harrison Lagat; Emily R Begnel; Julia C Dettinger; Grace John-Stewart; Jared M Baeten
Journal:  PLoS Med       Date:  2019-09-03       Impact factor: 11.069
  9 in total
  3 in total

1.  Tenofovir Diphosphate Concentrations in Dried Blood Spots From Pregnant and Postpartum Adolescent and Young Women Receiving Daily Observed Pre-exposure Prophylaxis in Sub-Saharan Africa.

Authors:  Lynda Stranix-Chibanda; Peter L Anderson; Deborah Kacanek; Sybil Hosek; Sharon Huang; Teacler G Nematadzira; Frank Taulo; Violet Korutaro; Clemensia Nakabiito; Maysebole Masenya; Kathryn Lypen; Emily Brown; Mustafa E Ibrahim; Jenna Yager; Lubbe Wiesner; Benjamin Johnston; K Rivet Amico; James F Rooney; Nahida Chakhtoura; Hans M L Spiegel; Benjamin H Chi
Journal:  Clin Infect Dis       Date:  2021-10-05       Impact factor: 20.999

2.  Implementation strategies for integrating pre-exposure prophylaxis for HIV prevention and family planning services for adolescent girls and young women in Kenya: a qualitative study.

Authors:  Stephanie D Roche; Gena Barnabee; Victor Omollo; Felix Mogaka; Josephine Odoyo; Elizabeth A Bukusi; Jennifer F Morton; Rachel Johnson; Connie Celum; Jared M Baeten; Gabrielle O'Malley
Journal:  BMC Health Serv Res       Date:  2022-03-30       Impact factor: 2.655

3.  Brief Report: Quantifiable Plasma Tenofovir Among South African Women Using Daily Oral Pre-exposure Prophylaxis During the ECHO Trial.

Authors:  Ivana Beesham; Leila E Mansoor; Dvora L Joseph Davey; Thesla Palanee-Phillips; Jenni Smit; Khatija Ahmed; Pearl Selepe; Cheryl Louw; Mandisa Singata-Madliki; Philip Kotze; Renee Heffron; Urvi M Parikh; Lubbe Wiesner; Helen Rees; Jared M Baeten; Mags Beksinska
Journal:  J Acquir Immune Defic Syndr       Date:  2022-06-09       Impact factor: 3.771
  3 in total

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