Literature DB >> 321076

Metronidazole in prevention and treatment of bacteroides infections in elective colonic surgery.

A T Willis, I R Ferguson, P H Jones, K D Phillips, P V Tearle, R V Fiddian, D F Graham, D H Harland, D F Hughes, D Knight, W M Mee, N Pashby, R L Rothwell-Jackson, A K Sachdeva, I Sutch, C Kilbey, D Edwards.   

Abstract

A double-blind randomised trial was carried out among 46 patients undergoing elective colonic surgery; 27 patients received prophylactic metronidazole and 19 received placebo. Anaerobic infections did not develop in any of the metronidazole-treated patients, but did develop in 11 (58%) of 19 controls who were subsequently successfully treated with metronidazole.

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Year:  1977        PMID： 321076      PMCID： PMC1605270          DOI： 10.1136/bmj.1.6061.607

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  11 in total

1.  Rapid diagnosis of anaerobic infections by gas-liquid chromatography of clinical material.

Authors:  K D Phillips; P V Tearle; A T Willis
Journal:  J Clin Pathol       Date:  1976-05       Impact factor: 3.411

2.  Effect of preoperative neomycin-erythromycin intestinal preparation on the incidence of infectious complications following colon surgery.

Authors:  R L Nichols; P Broido; R E Condon; S L Gorbach; L M Nyhus
Journal:  Ann Surg       Date:  1973-10       Impact factor: 12.969

3.  The value of a plastic adhesive drape in the prevention of wound infection. A controlled trial.

Authors:  D W Jackson; A V Pollock; D S Tindal
Journal:  Br J Surg       Date:  1971-05       Impact factor: 6.939

4.  A bacteriological study of the immediate environment of a surgical wound.

Authors:  A I Davidson; G Smith; H G Smylie
Journal:  Br J Surg       Date:  1971-05       Impact factor: 6.939

5.  Wound infections due to Bacteroides fragilis following intestinal surgery.

Authors:  D A Leigh
Journal:  Br J Surg       Date:  1975-05       Impact factor: 6.939

6.  Single-dose peroperative antibiotic prophylaxis in gastrointestinal surgery.

Authors:  D A Griffiths; R A Simpson; B A Shorey; D C Speller; N B Williams
Journal:  Lancet       Date:  1976-08-14       Impact factor: 79.321

7.  Short term routine antibiotic prophylaxis in surgery.

Authors:  E J Stokes; P M Waterworth; V Franks; B Watson; C G Clark
Journal:  Br J Surg       Date:  1974-09       Impact factor: 6.939

8.  Prophylactic oral antimicrobial agents in elective colonic surgery. A controlled trial.

Authors:  J Goldring; W McNaught; A Scott; G Gillespie
Journal:  Lancet       Date:  1975-11-22       Impact factor: 79.321

9.  Prophylaxis against anaerobic sepsis in bowel surgery.

Authors:  M R Keighley; A R Crapp; D W Burdon; W T Cooke; J Alexander-Williams
Journal:  Br J Surg       Date:  1976-07       Impact factor: 6.939

10.  Bacterial flora of the appendix fossa in appendicitis and postoperative wound infection.

Authors:  D A Leigh; K Simmons; E Norman
Journal:  J Clin Pathol       Date:  1974-12       Impact factor: 3.411
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  25 in total

Review 1.  Antibiotics in colorectal surgery.

Authors:  S J Eykyn
Journal:  Ann R Coll Surg Engl       Date:  1990-05       Impact factor: 1.891

Review 2.  Canadian consensus statement: enhanced recovery after surgery in bariatric surgery.

Authors:  Jerry T Dang; Vivian G Szeto; Ahmad Elnahas; James Ellsmere; Allan Okrainec; Amy Neville; Samaad Malik; Ekua Yorke; Dennis Hong; Laurent Biertho; Timothy Jackson; Shahzeer Karmali
Journal:  Surg Endosc       Date:  2019-06-17       Impact factor: 4.584

Review 3.  Review of general surgery 1977.

Authors:  H Ellis
Journal:  Postgrad Med J       Date:  1978-06       Impact factor: 2.401

Review 4.  Prevention of infection in surgical wounds.

Authors:  M R Keighley
Journal:  Ann R Coll Surg Engl       Date:  1978-05       Impact factor: 1.891

5.  The incidence of wound sepsis in a community hospital.

Authors:  M K O'Malley; J P Duignan; J S Lavelle
Journal:  Ir J Med Sci       Date:  1984-04       Impact factor: 1.568

6.  Vaginitis revisited.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1981-09-19

7.  Dip slide culture of intraoperative peritoneal irrigation fluid for prediction of septic complication in elective colorectal surgery.

Authors:  B E Claesson; D E Holmlund
Journal:  J Clin Microbiol       Date:  1986-12       Impact factor: 5.948

8.  Determinants of wound infection after colon surgery.

Authors:  E Simchen; M Shapiro; T G Sacks; J Michel; A Durst; Z Eyal
Journal:  Ann Surg       Date:  1984-03       Impact factor: 12.969

9.  The identification of gram-negative anaerobic bacilli isolated from clinical infections.

Authors:  B I Duerden
Journal:  J Hyg (Lond)       Date:  1980-04

10.  Metronidazole decreases viability of DLD-1 colorectal cancer cell line.

Authors:  Anna Sadowska; Rafał Krętowski; Beata Szynaka; Marzanna Cechowska-Pasko; Halina Car
Journal:  Cancer Biother Radiopharm       Date:  2013-06-18       Impact factor: 3.099
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