Literature DB >> 32105730

ncEP: A Manually Curated Database for Experimentally Validated ncRNA-encoded Proteins or Peptides.

Haizhou Liu1, Xu Zhou1, Mengqin Yuan1, Shunheng Zhou1, Yu-E Huang1, Fei Hou1, Xiaofeng Song2, Lihong Wang3, Wei Jiang4.   

Abstract

Noncoding RNAs (ncRNAs), such as lncRNAs, circRNAs and pri-miRNAs, play important roles in physiological and pathological processes. Recently, it was demonstrated that they could encode proteins or peptides. However, relevant information is scattered across numerous published articles, which is inconvenient for the exploration of ncRNA translation by researchers. In this study, we presented an ncEP database, which records the low-throughput experimentally validated (LTEV) proteins or peptides encoded by ncRNAs, from published articles. Collectively, ncEP contains 80 entries including 74 proteins or peptides, 22 lncRNAs, 11 circRNAs, 9 pri-miRNAs and 37 other ncRNAs across 18 species from more than 50 articles of over 2000 candidate articles. We have provided a user-friendly interface for users to search, browse, visualize, download and submit data. In summary, ncEP provides a relatively comprehensive repository of the LTEV proteins or peptides encoded by ncRNAs and will enrich the knowledge for translation process. ncEP is freely available at http://www.jianglab.cn/ncEP/.
Copyright © 2020 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  circRNA; lncRNA; ncRNA; peptide; translation

Year:  2020        PMID: 32105730     DOI: 10.1016/j.jmb.2020.02.022

Source DB:  PubMed          Journal:  J Mol Biol        ISSN: 0022-2836            Impact factor:   5.469


  8 in total

1.  LncRNA-Encoded Short Peptides Identification Using Feature Subset Recombination and Ensemble Learning.

Authors:  Siyuan Zhao; Jun Meng; Yushi Luan
Journal:  Interdiscip Sci       Date:  2021-07-25       Impact factor: 2.233

Review 2.  Noncoding RNAs in subchondral bone osteoclast function and their therapeutic potential for osteoarthritis.

Authors:  Li Duan; Yujie Liang; Xiao Xu; Jifeng Wang; Xingfu Li; Deshun Sun; Zhiqin Deng; Wencui Li; Daping Wang
Journal:  Arthritis Res Ther       Date:  2020-11-25       Impact factor: 5.156

Review 3.  Coding of Non-coding RNA: Insights Into the Regulatory Functions of Pri-MicroRNA-Encoded Peptides in Plants.

Authors:  Yi Ren; Yue Song; Lipeng Zhang; Dinghan Guo; Juan He; Lei Wang; Shiren Song; Wenping Xu; Caixi Zhang; Amnon Lers; Chao Ma; Shiping Wang
Journal:  Front Plant Sci       Date:  2021-02-25       Impact factor: 5.753

4.  LncPep: A Resource of Translational Evidences for lncRNAs.

Authors:  Teng Liu; Jingni Wu; Yangjun Wu; Wei Hu; Zhixiao Fang; Zishan Wang; Chunjie Jiang; Shengli Li
Journal:  Front Cell Dev Biol       Date:  2022-01-24

Review 5.  Two Worlds Colliding: The Interplay Between Natural Compounds and Non-Coding Transcripts in Cancer Therapy.

Authors:  Alexandru A Sabo; Maria Dudau; George L Constantin; Tudor C Pop; Christoph-M Geilfus; Alessio Naccarati; Mihnea P Dragomir
Journal:  Front Pharmacol       Date:  2021-07-06       Impact factor: 5.810

6.  SPENCER: a comprehensive database for small peptides encoded by noncoding RNAs in cancer patients.

Authors:  Xiaotong Luo; Yuantai Huang; Huiqin Li; Yihai Luo; Zhixiang Zuo; Jian Ren; Yubin Xie
Journal:  Nucleic Acids Res       Date:  2022-01-07       Impact factor: 16.971

7.  TransLnc: a comprehensive resource for translatable lncRNAs extends immunopeptidome.

Authors:  Dezhong Lv; Zhenghong Chang; Yangyang Cai; Junyi Li; Liping Wang; Qiushuang Jiang; Kang Xu; Na Ding; Xia Li; Juan Xu; Yongsheng Li
Journal:  Nucleic Acids Res       Date:  2022-01-07       Impact factor: 16.971

Review 8.  The Role of N6 -Methyladenosine Modified Circular RNA in Pathophysiological Processes.

Authors:  Mei Tang; Yonggang Lv
Journal:  Int J Biol Sci       Date:  2021-06-01       Impact factor: 6.580

  8 in total

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