Literature DB >> 321035

Selectively deuterated amino acid analogues. Synthesis, incorporation into proteins and NMR properties.

H R Matthews, K S Matthews, S J Opella.   

Abstract

Selectively deuterated analogues of histidine, tyrosine, phenylalanine and tryptophan have been synthesized by chemical exchange. These analogues have been characterized by NMR spectrometry and used for growth of bacteria. Active lactose repressor protein has been isolated from cells grown on the deuterated amino acids, and denatured 1H and 2H NMR spectra have been determined for the protein.

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Year:  1977        PMID： 321035     DOI： 10.1016/0304-4165(77)90134-9

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  11 in total

1.  Hydrogen-deuterium exchange of aromatic amines and amides using deuterated trifluoroacetic acid.

Authors:  Richard Giles; Amy Lee; Erica Jung; Aaron Kang; Kyung Woon Jung
Journal:  Tetrahedron Lett       Date:  2015-01-28       Impact factor: 2.415

2.  Actin dynamics studied by solid-state NMR spectroscopy.

Authors:  L Phillips; F Separovic; B A Cornell; J A Barden; C G dos Remedios
Journal:  Eur Biophys J       Date:  1991       Impact factor: 1.733

3.  19F NMR relaxation studies on 5-fluorotryptophan- and tetradeutero-5-fluorotryptophan-labeled E. coli glucose/galactose receptor.

Authors:  L A Luck; J E Vance; T M O'Connell; R E London
Journal:  J Biomol NMR       Date:  1996-06       Impact factor: 2.835

4.  The association of the kynurenine pathway of tryptophan metabolism with acute brain dysfunction during critical illness*.

Authors:  Jessica R Adams Wilson; Alessandro Morandi; Timothy D Girard; Jennifer L Thompson; Chad S Boomershine; Ayumi K Shintani; E Wesley Ely; Pratik P Pandharipande
Journal:  Crit Care Med       Date:  2012-03       Impact factor: 7.598

5.  Functional conformation changes in the TF(1)-ATPase beta subunit probed by 12 tyrosine residues.

Authors:  H Yagi; K Tozawa; N Sekino; T Iwabuchi; M Yoshida; H Akutsu
Journal:  Biophys J       Date:  1999-10       Impact factor: 4.033

6.  Analysis of biogenic amines in plasma of hypertensive patients and a control group.

Authors:  R Andrew; S A Best; D G Watson; J M Midgley; J L Reid; I B Squire
Journal:  Neurochem Res       Date:  1993-11       Impact factor: 3.996

7.  An Unusual Route for p-Aminobenzoate Biosynthesis in Chlamydia trachomatis Involves a Probable Self-Sacrificing Diiron Oxygenase.

Authors:  Yamilet Macias-Orihuela; Thomas Cast; Ian Crawford; Kevin J Brandecker; Jennifer J Thiaville; Alexey G Murzin; Valérie de Crécy-Lagard; Robert H White; Kylie D Allen
Journal:  J Bacteriol       Date:  2020-09-23       Impact factor: 3.490

8.  Protein dynamics by solid-state NMR: aromatic rings of the coat protein in fd bacteriophage.

Authors:  C M Gall; T A Cross; J A DiVerdi; S J Opella
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205

9.  Kinetic study on p-tyramine metabolism in humans using stable isotope-labeled tracers.

Authors:  M Shimamura; H Kodaka; T Hayashi; H Naruse
Journal:  Neurochem Res       Date:  1993-06       Impact factor: 3.996

10.  H-D exchange in deuterated trifluoroacetic acid via ligand-directed NHC-palladium catalysis: a powerful method for deuteration of aromatic ketones, amides, and amino acids.

Authors:  Richard Giles; Green Ahn; Kyung Woon Jung
Journal:  Tetrahedron Lett       Date:  2015-11-04       Impact factor: 2.415
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