Literature DB >> 32102764

Replacing one evil with another: Is the fibula really a dispensable spare part available for transfer in patients with medication-related osteonecrosis of the jaws?

Jan-Dirk Raguse1, Andrej Trampuz2, Marcelo Sanchez Boehm3, Susanne Nahles1, Benedicta Beck-Broichsitter1, Max Heiland1, Norbert Neckel4.   

Abstract

Because of the long-term and consecutive use of different causative agents, clinicians are increasingly encountering patients needing restoration of the stomatognathic system after surgical resection of highly advanced necroses of the jaw. For plastic restoration in these cases, microvascular reconstruction seems to represent the most viable option. According to the limited data available, the risks of this operation are considered comparable with those faced by other patient cohorts. We report here the case of a patient who suffered 2 successive pathologic fractures of the tibia after microsurgical reconstruction of the mandible with a free fibula flap. This exemplifies a general problem, especially because the patient also suffered from a treatment-refractory infection of the transplanted bone. Although the present literature indicates otherwise, fibula transplants might not be the gold standard in these cases. Therefore, alternatives to transplants from the weight-bearing parts of the body need to be considered until more data are available.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2020        PMID: 32102764     DOI: 10.1016/j.oooo.2019.10.008

Source DB:  PubMed          Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol


  3 in total

1.  Targeted histological evaluation shows high incidence of actinomyces infection in medication-related osteonecrosis of the jaws.

Authors:  Andrea Brody; Bálint Scheich; Csaba Dobo-Nagy
Journal:  Sci Rep       Date:  2022-03-01       Impact factor: 4.996

2.  Sonication versus the conventional method for evaluation of the dental microbiome: a prospective pilot study.

Authors:  Oliver Wagendorf; Peter Menzel; Rolf Schwarzer; Norbert Neckel; Saskia Preissner; Max Heiland; Susanne Nahles
Journal:  BMC Oral Health       Date:  2022-08-12       Impact factor: 3.747

3.  Mandibular Reconstruction with Free Fibula Flap for Medication-related Osteonecrosis of the Jaw in Patients with Multiple Myeloma.

Authors:  Christodoulos Kaoutzanis; Jason W Yu; Z-Hye Lee; Ashkan Davary; Kenneth E Fleisher; Jamie P Levine
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-10-28
  3 in total

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