Literature DB >> 3210193

Modulating the oxygen tension in tumours by hypothermia and hyperbaric oxygen.

A H Nias1, P M Perry, A R Photiou.   

Abstract

Hypothermia is associated with reduced metabolism of tissues and especially reduced oxygen consumption by tumours. If the blood supply to a hypothermic tumour can be maintained then the hypoxic fraction of cells should be reduced and the radiation response increased. This hypothesis has been tested with radiation under hyperbaric oxygen and increased tumour response has been demonstrated.

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Year:  1988        PMID： 3210193      PMCID： PMC1291839          DOI： 10.1177/014107688808101106

Source DB:  PubMed          Journal:  J R Soc Med        ISSN： 0141-0768            Impact factor:   18.000


  7 in total

1.  Regional blood flow by fractional distribution of indicators.

Authors:  L A SAPIRSTEIN
Journal:  Am J Physiol       Date:  1958-04

2.  Carcinoma of the cervix--anaemia, radiotherapy and hyperbaric oxygen.

Authors:  S Dische; P J Anderson; R Sealy; E R Watson
Journal:  Br J Radiol       Date:  1983-04       Impact factor: 3.039

3.  A feasibility study of a new approach to clinical radiosensitisation: hypothermia and hyperbaric oxygen in combination with pharmacological vasodilatation.

Authors:  R Sealy; G G Harrison; D Morrell; J Korrubel; A Gregory; L Barry; G Blekkenhorst; E R Hering; A B Fataar; J Boniaszczuk
Journal:  Br J Radiol       Date:  1986-11       Impact factor: 3.039

4.  The use of ketamine plus diazepam anaesthesia to increase the radiosensitivity of a C3H mouse mammary adenocarcinoma in hyperbaric oxygen.

Authors:  G M Tozer; M Penhaligon; A H Nias
Journal:  Br J Radiol       Date:  1984-01       Impact factor: 3.039

5.  Abnormal response of tumor vasculature to vasoactive drugs.

Authors:  R C Chan; C F Babbs; R J Vetter; C H Lamar
Journal:  J Natl Cancer Inst       Date:  1984-01       Impact factor: 13.506

6.  Effect of hypothermia on radiosensitization.

Authors:  A H Nias; P Perry; A Photiou; K Reghebi
Journal:  Int J Radiat Biol Relat Stud Phys Chem Med       Date:  1986-08

7.  The histological structure of some human lung cancers and the possible implications for radiotherapy.

Authors:  R H THOMLINSON; L H GRAY
Journal:  Br J Cancer       Date:  1955-12       Impact factor: 7.640
  7 in total
  3 in total

1.  Concurrent Longitudinal EPR Monitoring of Tissue Oxygenation, Acidosis, and Reducing Capacity in Mouse Xenograft Tumor Models.

Authors:  Andrey A Bobko; Jason Evans; Nicholas C Denko; Valery V Khramtsov
Journal:  Cell Biochem Biophys       Date:  2016-05-18       Impact factor: 2.194

2.  Fever-range hyperthermia vs. hypothermia effect on cancer cell viability, proliferation and HSP90 expression.

Authors:  Dimitra Kalamida; Ilias V Karagounis; Achilleas Mitrakas; Sofia Kalamida; Alexandra Giatromanolaki; Michael I Koukourakis
Journal:  PLoS One       Date:  2015-01-30       Impact factor: 3.240

3.  Localized hypothermia: impact on oxygenation, microregional perfusion, metabolic and bioenergetic status of subcutaneous rat tumours.

Authors:  D K Kelleher; C Nauth; O Thews; W Krueger; P Vaupel
Journal:  Br J Cancer       Date:  1998-07       Impact factor: 7.640
  3 in total

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