The 'Expiry Problem' of broad consent for biobank research - And why a meta consent model solves it.

In this response to Neil Manson's latest intervention in our debate about the best consent model for biobank research we show, contra Manson that the 'expiry problem' that affects broad consent models because of changes over time in methods, purposes, types of data used and governance structures is a real and significant problem. We further show that our preferred implementation of meta consent as a national consent platform solves this problem and is not subject to the cost and burden objections that Manson raises. © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.