| Literature DB >> 32093305 |
Daria Lytkina1, Anastasiya Gutsalova1, Dmitriy Fedorishin1, Natalya Korotchenko1, Rafik Akhmedzhanov1,2, Vladimir Kozik1, Irina Kurzina1.
Abstract
Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone implants based on hydroxyapatite modified with zinc ions. Zinc-modified hydroxyapatite was composed and synthesized. Using the XRD method, the phase composition was established. Using SEM, EPMA, and low-temperature nitrogen adsorption (BET) methods, surface properties were investigated. Antibacterial activity and biocompatibility have been established. The studied materials have antimicrobial activity; the samples did not cause significant changes in either the internal organs or the general condition of laboratory animals during the entire experiment.Entities:
Keywords: biological activity; phase composition; zinc-modified hydroxyapatite
Year: 2020 PMID: 32093305 DOI: 10.3390/jfb11010010
Source DB: PubMed Journal: J Funct Biomater ISSN: 2079-4983