Literature DB >> 32091470

Confederates in the Attic: Posttraumatic Stress Disorder, Cardiovascular Disease, and the Return of Soldier's Heart.

J Douglas Bremner, Matthew T Wittbrodt1, Amit J Shah, Bradley D Pearce2, Nil Z Gurel3, Omer T Inan, Paolo Raggi4, Tené T Lewis2, Arshed A Quyyumi5, Viola Vaccarino.   

Abstract

Da Costa originally described Soldier's Heart in the 19th Century as a syndrome that occurred on the battlefield in soldiers of the American Civil War. Soldier's Heart involved symptoms similar to modern day posttraumatic stress disorder (PTSD) as well as exaggerated cardiovascular reactivity felt to be related to an abnormality of the heart. Interventions were appropriately focused on the cardiovascular system. With the advent of modern psychoanalysis, psychiatric symptoms became divorced from the body and were relegated to the unconscious. Later, the physiology of PTSD and other psychiatric disorders was conceived as solely residing in the brain. More recently, advances in psychosomatic medicine led to the recognition of mind-body relationships and the involvement of multiple physiological systems in the etiology of disorders, including stress, depression PTSD, and cardiovascular disease, has moved to the fore, and has renewed interest in the validity of the original model of the Soldier's Heart syndrome.

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Year:  2020        PMID: 32091470      PMCID: PMC8214871          DOI: 10.1097/NMD.0000000000001100

Source DB:  PubMed          Journal:  J Nerv Ment Dis        ISSN: 0022-3018            Impact factor:   2.254


  162 in total

1.  Sensitization of the startle reflex by footshock: blockade by lesions of the central nucleus of the amygdala or its efferent pathway to the brainstem.

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Journal:  Behav Neurosci       Date:  1989-06       Impact factor: 1.912

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4.  Physical and mental comorbidity, disability, and suicidal behavior associated with posttraumatic stress disorder in a large community sample.

Authors:  Jitender Sareen; Brian J Cox; Murray B Stein; Tracie O Afifi; Claire Fleet; Gordon J G Asmundson
Journal:  Psychosom Med       Date:  2007-03-30       Impact factor: 4.312

5.  Neurons in medial prefrontal cortex signal memory for fear extinction.

Authors:  Mohammed R Milad; Gregory J Quirk
Journal:  Nature       Date:  2002-11-07       Impact factor: 49.962

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Authors:  J Douglas Bremner; Meena Vythilingam; Eric Vermetten; Nadeem Afzal; Ahsan Nazeer; John W Newcomer; Dennis S Charney
Journal:  Psychiatry Res       Date:  2004-11-30       Impact factor: 3.222

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Authors:  J D Bremner; M Vythilingam; E Vermetten; J Adil; S Khan; A Nazeer; N Afzal; T McGlashan; B Elzinga; G M Anderson; G Heninger; S M Southwick; D S Charney
Journal:  Psychoneuroendocrinology       Date:  2003-08       Impact factor: 4.905

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Authors:  R C Kessler; A Sonnega; E Bromet; M Hughes; C B Nelson
Journal:  Arch Gen Psychiatry       Date:  1995-12

10.  Quantifying acute physiological biomarkers of transcutaneous cervical vagal nerve stimulation in the context of psychological stress.

Authors:  Nil Z Gurel; Minxuan Huang; Matthew T Wittbrodt; Hewon Jung; Stacy L Ladd; Md Mobashir H Shandhi; Yi-An Ko; Lucy Shallenberger; Jonathon A Nye; Bradley Pearce; Viola Vaccarino; Amit J Shah; J Douglas Bremner; Omer T Inan
Journal:  Brain Stimul       Date:  2019-08-06       Impact factor: 8.955

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  1 in total

1.  Estrogen Protects Vasomotor Functions in Rats During Catecholamine Stress.

Authors:  Lin Zhang; Chenfei Li; Liting Yang; Gabriel Komla Adzika; Jeremiah Ong'achwa Machuki; Mingjin Shi; Qi Sun; Hong Sun
Journal:  Front Cardiovasc Med       Date:  2021-06-16
  1 in total

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