Literature DB >> 32089233

Pharmacological effects of icariin.

Chunyang He1, Ze Wang2, Jingshan Shi3.   

Abstract

Icariin (ICA) is a principal active component from traditional Chinese medicine Epimedium grandiflorum. To explain its traditional medical usages by modern science, a variety of pharmacological effects have been studied for ICA. In this review, we summarized the pharmacokinetics of ICA as well as its pharmacological mechanisms in neurodegenerative disease, cardiovascular disease, anti-osteoporosis, anti-inflammation, anti-oxidative stress, anti-depression and anti-tumors.
© 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cardiovascular disease; Icariin; Neurodegenerative disease; Pharmacokinetics; Pharmacology; Traditional Chinese medicine

Mesh：

Substances：

Year:  2020        PMID： 32089233     DOI： 10.1016/bs.apha.2019.10.004

Source DB:  PubMed          Journal:  Adv Pharmacol        ISSN： 1054-3589


  25 in total

1.  Current update on anticancer effects of icariin: A journey of the last ten years.

Authors:  Mukta Gupta; Yachana Mishra; Vijay Mishra; Murtaza M Tambuwala
Journal:  EXCLI J       Date:  2022-04-06       Impact factor: 4.022

Review 2.  Pyroptosis and Intervertebral Disc Degeneration: Mechanistic Insights and Therapeutic Implications.

Authors:  Yuying Ge; Yuying Chen; Chijiao Guo; Huan Luo; Fangda Fu; Weifeng Ji; Chengliang Wu; Hongfeng Ruan
Journal:  J Inflamm Res       Date:  2022-10-17

3.  A Placebo-Controlled, Pseudo-Randomized, Crossover Trial of Botanical Agents for Gulf War Illness: Reishi Mushroom (Ganoderma lucidum), Stinging Nettle (Urtica dioica), and Epimedium (Epimedium sagittatum).

Authors:  Jarred Younger; Emily K Donovan; Kathleen S Hodgin; Timothy J Ness
Journal:  Int J Environ Res Public Health       Date:  2021-04-01       Impact factor: 3.390

Review 4.  The Potential Properties of Natural Compounds in Cardiac Stem Cell Activation: Their Role in Myocardial Regeneration.

Authors:  Cristina Carresi; Miriam Scicchitano; Federica Scarano; Roberta Macrì; Francesca Bosco; Saverio Nucera; Stefano Ruga; Maria Caterina Zito; Rocco Mollace; Lorenza Guarnieri; Anna Rita Coppoletta; Micaela Gliozzi; Vincenzo Musolino; Jessica Maiuolo; Ernesto Palma; Vincenzo Mollace
Journal:  Nutrients       Date:  2021-01-19       Impact factor: 5.717

5.  Icariside II promotes the differentiation of human amniotic mesenchymal stem cells into dopaminergic neuron-like cells.

Authors:  Wei Kuang; Tao Liu; Fang He; Limei Yu; Qian Wang; Changyin Yu
Journal:  In Vitro Cell Dev Biol Anim       Date:  2021-03-15       Impact factor: 2.416

Review 6.  Gut Microbiota: A Novel Regulator of Cardiovascular Disease and Key Factor in the Therapeutic Effects of Flavonoids.

Authors:  Qinyu Li; Bing Gao; Bateer Siqin; Qian He; Ru Zhang; Xiangxi Meng; Naiheng Zhang; Na Zhang; Minhui Li
Journal:  Front Pharmacol       Date:  2021-06-16       Impact factor: 5.810

7.  Optimized Icariin Phytosomes Exhibit Enhanced Cytotoxicity and Apoptosis-Inducing Activities in Ovarian Cancer Cells.

Authors:  Nabil A Alhakamy; Usama A Fahmy; Shaimaa M Badr-Eldin; Osama A A Ahmed; Hani Z Asfour; Hibah M Aldawsari; Mardi M Algandaby; Basma G Eid; Ashraf B Abdel-Naim; Zuhier A Awan; Nabil K Alruwaili; Amir I Mohamed
Journal:  Pharmaceutics       Date:  2020-04-11       Impact factor: 6.321

Review 8.  Nutraceuticals in the Prevention of Neonatal Hypoxia-Ischemia: A Comprehensive Review of their Neuroprotective Properties, Mechanisms of Action and Future Directions.

Authors:  Marta Reyes-Corral; Noelia Sola-Idígora; Rocío de la Puerta; Joan Montaner; Patricia Ybot-González
Journal:  Int J Mol Sci       Date:  2021-03-03       Impact factor: 5.923

9.  Back to nature: herbal treatment, environmental enrichment, and social play can protect against unpredictable chronic stress in Long-Evans rats (Rattus norvegicus).

Authors:  Kiana Nwachukwu; Elizabeth Rhoads; Sarah Meek; Massimo Bardi
Journal:  Psychopharmacology (Berl)       Date:  2021-08-01       Impact factor: 4.530

10.  Icariin Ameliorates Diabetic Renal Tubulointerstitial Fibrosis by Restoring Autophagy via Regulation of the miR-192-5p/GLP-1R Pathway.

Authors:  Zhirong Jia; Kaiwei Wang; Yameng Zhang; Yalei Duan; Kang Xiao; Shuo Liu; Xuansheng Ding
Journal:  Front Pharmacol       Date:  2021-07-19       Impact factor: 5.810
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.