| Literature DB >> 32082469 |
Francisco Javier Lira-Valero1, Nancy Pulido-Díaz1, Marissa De Jesús Quintal-Ramírez1.
Abstract
BACKGROUND: Langerhans cell histiocytosis (LCH) is a neoplasm of the monocyte-macrophage lineage, characterized by clonal proliferation and dissemination of cells that express CD1a+ and CD207. It is a disorder that predominates in childhood. Although the skin is the second most frequently affected organ (30-60%), isolated cutaneous involvement is rare; its frequency does not exceed 4 to 12 percent of cases. Single system-LCH usually has a good prognosis. We describe a case of LCH with isolated cutaneous involvement that presented in an adult patient and was refractory to polychemotherapy.Entities:
Keywords: Langerhans cell; cutaneous; histiocytosis
Year: 2020 PMID: 32082469 PMCID: PMC7028377
Source DB: PubMed Journal: J Clin Aesthet Dermatol ISSN: 1941-2789