Miguel Angel Martinez-García1, Carmen Villa2, Yadira Dobarganes2, Rosa Girón3, Luis Maíz4, Marta García-Clemente5, Oriol Sibila6, Rafael Golpe7, Juan Rodríguez8, Esther Barreiro9, Juan Luis Rodriguez10, Rosario Menéndez11, Concepción Prados12, David de la Rosa13, Casilda Olveira14. 1. Servicio de Neumología, Hospital Universitario y Politécnico La Fe, Valencia, España. Electronic address: mianmartinezgarcia@gmail.com. 2. Servicio de Neumología, Clínica Fuensanta, Madrid, España. 3. Servicio de Neumología, Instituto de Investigación Sanitaria, Hospital Universitario de la Princesa, Madrid, España. 4. Servicio de Neumología, Hospital Ramón y Cajal, Madrid, España. 5. Servicio de Neumología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España. 6. Servicio de Neumología, Hospital Clínico, Barcelona, España. 7. Servicio de Neumología, Hospital Lucus Augusti, Lugo, España. 8. Servicio de Neumología, Hospital San Agustín, Avilés, Asturias, España. 9. Servicio de Neumología, Hospital del Mar-IMIM, UPF, CIBERES, Barcelona, España. 10. Servicio de Neumología, Hospital San Carlos, Madrid, España. 11. Servicio de Neumología, Hospital Universitario y Politécnico La Fe, Valencia, España. 12. Servicio de Neumología, Hospital La Paz, Madrid, España. 13. Servicio de Neumología, Hospital Santa Creu i Sant Pau, Barcelona, España. 14. Servicio de Neumología, Hospital Regional Universitario de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA)/Universidad de Málaga, Málaga, España.
Abstract
INTRODUCTION: The SEPAR Spanish Bronchiectasis Registry (RIBRON) began as a platform for the collection of longitudinal data on patients with this disease. The objective of this study is to describe its operation and to analyze the characteristics of bronchiectasis patients according to sex. METHODS: A total of 1912 adult patients diagnosed with bronchiectasis in 43 centers were included between February 2015 and 2019. All patients had complete data consisting of at least 79 basic required variables, controlled by an external audit. RESULTS: Mean age was 67.6 (15.2) years; 63.9% were women. The most common symptom was productive cough (78.3%) which was mucopurulent-purulent in 45.9% of cases. The most common etiology was post-infectious (40.4%), while 18.5% were idiopathic. Pseudomonas aeruginosa was the most frequently isolated microorganism (40.4%), of which 25.6% were associated with chronic infection. The annual number of mild-to-moderate/severe exacerbations was 1.62 (1.9)/0.59 (1.3). Half of the patients (50%) presented with airflow obstruction (17% severe). The most frequent radiological localization was lower lobes. The average FACED/E-FACED/BSI values were 2.06 (1.7)/2.67 (2.2)/7.8 (4.5), respectively. Overall, 66.7% of patients were taking inhaled corticosteroids, 19.2% macrolides, and 19.5% inhaled antibiotics. Women presented a less severe profile than men in clinical and functional terms, and a similar infectious, radiological and therapeutic profile. CONCLUSIONS: RIBRON represents an excellent map of the characteristics of bronchiectasis in our country. Two thirds of patients are women who presented lower disease severity as a specific characteristic.
INTRODUCTION: The SEPAR Spanish Bronchiectasis Registry (RIBRON) began as a platform for the collection of longitudinal data on patients with this disease. The objective of this study is to describe its operation and to analyze the characteristics of bronchiectasispatients according to sex. METHODS: A total of 1912 adult patients diagnosed with bronchiectasis in 43 centers were included between February 2015 and 2019. All patients had complete data consisting of at least 79 basic required variables, controlled by an external audit. RESULTS: Mean age was 67.6 (15.2) years; 63.9% were women. The most common symptom was productive cough (78.3%) which was mucopurulent-purulent in 45.9% of cases. The most common etiology was post-infectious (40.4%), while 18.5% were idiopathic. Pseudomonas aeruginosa was the most frequently isolated microorganism (40.4%), of which 25.6% were associated with chronic infection. The annual number of mild-to-moderate/severe exacerbations was 1.62 (1.9)/0.59 (1.3). Half of the patients (50%) presented with airflow obstruction (17% severe). The most frequent radiological localization was lower lobes. The average FACED/E-FACED/BSI values were 2.06 (1.7)/2.67 (2.2)/7.8 (4.5), respectively. Overall, 66.7% of patients were taking inhaled corticosteroids, 19.2% macrolides, and 19.5% inhaled antibiotics. Women presented a less severe profile than men in clinical and functional terms, and a similar infectious, radiological and therapeutic profile. CONCLUSIONS:RIBRON represents an excellent map of the characteristics of bronchiectasis in our country. Two thirds of patients are women who presented lower disease severity as a specific characteristic.
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