Literature DB >> 32080826

PVAT: an important guardian of the cardiovascular system.

Xiuying Liang1, Yan Qi1, Fan Dai1, Jingya Gu1, Wenjuan Yao2.   

Abstract

Perivascular adipose tissue (PVAT) had long been considered to serve only structural, vessel-supporting purposes, but today PVAT is recognized to be an endocrine organ with important physiological and pathological effects. The expansion of PVAT in vascular homeostasis and vascular disease has attracted much interest. PVAT has been shown to release a wide spectrum of molecules, such as PVAT-derived relaxing factors (PVATRFs) and PVAT-derived contracting factors (PVATCFs). PVAT dysfunction may lead to obesity, atherosclerosis, and other cardiovascular diseases. This review describes recent advances in our understanding of PVAT's important effects on the cardiovascular system.

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Year:  2020        PMID： 32080826     DOI： 10.14670/HH-18-211

Source DB:  PubMed          Journal:  Histol Histopathol        ISSN： 0213-3911            Impact factor:   2.303


  63 in total

1.  Perivascular Adipocytes Store Norepinephrine by Vesicular Transport.

Authors:  Maleeha F Ahmad; David Ferland; Nadia Ayala-Lopez; G Andres Contreras; Emma Darios; Janice Thompson; Alexander Ismail; Kyan Thelen; Adam J Moeser; Robert Burnett; Arun Anantharam; Stephanie W Watts
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-02       Impact factor: 8.311

Review 2.  Regulation of brown and beige fat by microRNAs.

Authors:  Yong Chen; Ruping Pan; Alexander Pfeifer
Journal:  Pharmacol Ther       Date:  2016-10-11       Impact factor: 12.310

3.  Obesity-Related Perivascular Adipose Tissue Damage Is Reversed by Sustained Weight Loss in the Rat.

Authors:  Charlotte E Bussey; Sarah B Withers; Robert G Aldous; Gillian Edwards; Anthony M Heagerty
Journal:  Arterioscler Thromb Vasc Biol       Date:  2016-05-12       Impact factor: 8.311

4.  Bmal1 in Perivascular Adipose Tissue Regulates Resting-Phase Blood Pressure Through Transcriptional Regulation of Angiotensinogen.

Authors:  Lin Chang; Wenhao Xiong; Xiangjie Zhao; Yanbo Fan; Yanhong Guo; Minerva Garcia-Barrio; Jifeng Zhang; Zhisheng Jiang; Jiandie D Lin; Y Eugene Chen
Journal:  Circulation       Date:  2018-01-25       Impact factor: 29.690

5.  Rictor in perivascular adipose tissue controls vascular function by regulating inflammatory molecule expression.

Authors:  Indranil Bhattacharya; Katja Drägert; Verena Albert; Emmanuel Contassot; Marlen Damjanovic; Asami Hagiwara; Lukas Zimmerli; Rok Humar; Michael N Hall; Edouard J Battegay; Elvira Haas
Journal:  Arterioscler Thromb Vasc Biol       Date:  2013-07-18       Impact factor: 8.311

6.  Loss of perivascular adipose tissue on peroxisome proliferator-activated receptor-γ deletion in smooth muscle cells impairs intravascular thermoregulation and enhances atherosclerosis.

Authors:  Lin Chang; Luis Villacorta; Rongxia Li; Milton Hamblin; Wei Xu; Chunyan Dou; Jifeng Zhang; Jiarui Wu; Rong Zeng; Y Eugene Chen
Journal:  Circulation       Date:  2012-08-01       Impact factor: 29.690

7.  Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease.

Authors:  Adam R Baker; Nancy F da Silva; David W Quinn; Alison L Harte; Domenico Pagano; Robert S Bonser; Sudhesh Kumar; Philip G McTernan
Journal:  Cardiovasc Diabetol       Date:  2006-01-13       Impact factor: 9.951

8.  Perivascular adipose tissue contains functional catecholamines.

Authors:  N Ayala-Lopez; M Martini; W F Jackson; E Darios; R Burnett; B Seitz; G D Fink; S W Watts
Journal:  Pharmacol Res Perspect       Date:  2014-06-01

9.  Perivascular Adipose Tissue's Impact on Norepinephrine-Induced Contraction of Mesenteric Resistance Arteries.

Authors:  Nadia Ayala-Lopez; Janice M Thompson; Stephanie W Watts
Journal:  Front Physiol       Date:  2017-02-08       Impact factor: 4.566

10.  β3 -Adrenoceptor stimulation of perivascular adipocytes leads to increased fat cell-derived NO and vascular relaxation in small arteries.

Authors:  Charlotte E Bussey; Sarah B Withers; Sophie N Saxton; Neil Bodagh; Robert G Aldous; Anthony M Heagerty
Journal:  Br J Pharmacol       Date:  2018-08-10       Impact factor: 8.739
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  1 in total

1.  Comparative Proteomic Analysis of tPVAT during Ang II Infusion.

Authors:  Xiuying Liang; Haijing Guan; Jingwen Sun; Yan Qi; Wenjuan Yao
Journal:  Biomedicines       Date:  2021-12-02
  1 in total

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