| Literature DB >> 3207759 |
P G Thomas1, A G Zimmermann, A J Verkleij.
Abstract
The calcium antagonist flunarizine is shown to be able to prevent particle aggregation, membrane aggregation and blebbing resulting from elevated calcium concentrations. The anti-ischemic effects of flunarizine may therefore result in part from its ability to directly interfere with calcium-membrane interactions and thus prevent the lethal membrane reorganizations which occur after a period of ischemia during intracellular calcium overload.Entities:
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Year: 1988 PMID： 3207759 DOI： 10.1016/0005-2736(88)90421-x
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002