| Literature DB >> 32076912 |
Shannon L Stewart1, Angela Celebre2, John P Hirdes3, Jeffrey W Poss3.
Abstract
Suicide is the second leading cause of death in adolescents within Canada. While several risk factors have been found to be associated with increased risk, appropriate decision-support tools are needed to identify children who are at highest risk for suicide and self-harm. The aim of the present study was to develop and validate a methodology for identifying children at heightened risk for self-harm and suicide. Ontario data based on the interRAI Child and Youth Mental Health Screener (ChYMH-S) were analyzed to develop a decision-support algorithm to identify young persons at risk for suicide or self-harm. The algorithm was validated with additional data from 59 agencies and found to be a strong predictor of suicidal ideation and self-harm. The RiSsK algorithm provides a psychometrically sound decision-support tool that may be used to identify children and youth who exhibit signs and symptoms noted to increase the likelihood of suicide and self-harm.Entities:
Keywords: Children’s mental health; Self-harm; Suicidal ideation; Suicide risk; interRAI
Mesh:
Year: 2020 PMID: 32076912 PMCID: PMC7554002 DOI: 10.1007/s10578-020-00968-9
Source DB: PubMed Journal: Child Psychiatry Hum Dev ISSN: 0009-398X
Fig. 1Risk of Suicide and Self-harm (RiSsK) decision tree diagram. DSS depression symptoms scale
Derivation results of Risk of Suicide and Self-harm (RiSsK) algorithm (N = 60,414)
| Scale label | % of sample | Mean risk | % severe, very severe, or imminent risk | Odds ratio | Low 95% confidence interval | High 95% confidence interval |
|---|---|---|---|---|---|---|
| 0 | 46.3 | 0.08 | 0.1 | Reference | ||
| 1 | 12.8 | 0.30 | 1.1 | 4.4 | 4.1 | 4.7 |
| 2 | 14.2 | 0.62 | 1.5 | 12.5 | 11.8 | 13.3 |
| 3 | 13.7 | 0.85 | 3.3 | 21.2 | 19.9 | 22.6 |
| 4 | 6.6 | 1.44 | 9.5 | 74.4 | 68.8 | 80.3 |
| 5 | 5.7 | 1.74 | 19.5 | 134.8 | 124.1 | 146.5 |
| 6 | 0.8 | 2.28 | 42.6 | 422.1 | 352.8 | 504.9 |
| c-statistic = 0.837 | ||||||
Validation results of Risk of Suicide and Self-harm (RiSsK) algorithm (N = 2117)
| Scale label | % of sample | Mean risk | % severe, very severe, or imminent risk | Odds ratio | Low 95% confidence interval | High 95% confidence interval |
|---|---|---|---|---|---|---|
| 0 | 49.1 | 0.10 | 0.2 | Reference | ||
| 1 | 13.0 | 0.34 | 0.7 | 3.9 | 2.7 | 5.5 |
| 2 | 14.9 | 0.67 | 1.6 | 11.8 | 8.6 | 16.9 |
| 3 | 11.8 | 0.82 | 2.8 | 16.0 | 11.5 | 22.1 |
| 4 | 6.2 | 1.44 | 10.6 | 61.7 | 41.2 | 92.5 |
| 5 | 4.2 | 1.73 | 20.2 | 111.0 | 69.1 | 178.2 |
| 6 | 0.8 | 2.63 | 50.0 | 683.0 | 253.0 | > 999.99 |
| c-statistic = 0.822 | ||||||
Sensitivity and specificity results for the derivation sample: mild, moderate, and severe
| RiSsK | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
|---|---|---|---|---|---|
| Predict | 1 + | 90.5 | 64.0 | 54.7 | 93.3 |
| 2 + | 81.1 | 78.4 | 64.4 | 89.6 | |
| 3 + | 60.1 | 89.4 | 73.1 | 82.3 | |
| 4 + | 35.1 | 97.6 | 87.4 | 75.7 | |
| Predict | 1 + | 96.2 | 52.8 | 23.9 | 98.9 |
| 2 + | 91.1 | 66.8 | 29.7 | 98.0 | |
| 3 + | 77.9 | 81.1 | 38.8 | 96.0 | |
| 4 + | 55.1 | 93.4 | 56.3 | 93.1 | |
| Predict | 1 + | 97.9 | 47.6 | 5.3 | 99.9 |
| 2 + | 93.0 | 60.6 | 6.7 | 99.7 | |
| 3 + | 86.0 | 75.1 | 9.4 | 99.4 | |
| 4 + | 70.6 | 88.7 | 15.9 | 99.0 |
PPV positive predictive value, NPV negative predictive value
High risk for derivation results of Risk of Suicide and Self-harm (RiSsK) algorithm by age
| Scale label | 7 and younger | 8 to 11 | 12 and older | |||
|---|---|---|---|---|---|---|
| % of sample | Odds ratio | % of sample | Odds ratio | % of sample | Odds ratio | |
| 0 | 66.0 | Ref | 59.9 | Ref | 34.1 | Ref |
| 1 | 23.4 | 5.6 | 16.8 | 5.3 | 7.8 | 3.6 |
| 2 | 3.7 | 16.3 | 9.3 | 15.4 | 19.6 | 9.5 |
| 3 | 5.1 | 26.6 | 9.2 | 25.8 | 18.3 | 16.1 |
| 4 | 0.7 | 67.7 | 2.3 | 101.0 | 10.3 | 55.9 |
| 5 | 1.1 | 140.3 | 2.2 | 155.2 | 8.7 | 104.1 |
| 6 | 0.1 | 872.4 | 0.3 | 436.9 | 1.2 | 329.1 |
| c-statistic | 0.789 | 0.831 | 0.815 | |||
High risk for derivation results of Risk of Suicide and Self-harm (RiSsK) algorithm by sex
| Scale label | Males | Females | ||
|---|---|---|---|---|
| % of sample | Odds ratio | % of sample | Odds ratio | |
| 0 | 54.0 | Ref | 38.7 | Ref |
| 1 | 15.7 | 4.2 | 9.9 | 4.6 |
| 2 | 12.1 | 11.1 | 16.3 | 14.7 |
| 3 | 10.7 | 19.1 | 16.6 | 24.4 |
| 4 | 3.8 | 70.3 | 9.3 | 84.8 |
| 5 | 3.3 | 113.8 | 8.1 | 160.4 |
| 6 | 0.4 | 429.3 | 1.1 | 472.7 |
| c-statistic | 0.819 | 0.841 | ||
High risk for derivation results of Risk of Suicide and Self-harm (RiSsK) algorithm by DSM diagnosis
| DSM-IVaN = 25,104 full ChYMH or ChYMH-DD | RiSsK 2 + | RiSsK 3 + | ||
|---|---|---|---|---|
| Most important dx (%) | Any importance (%) | Most important dx (%) | Any importance (%) | |
| Reactive attachment | 48.5 | 54.8 | 32.4 | 35.6 |
| Attention deficit hyperactivity | 34.0 | 39.9 | 16.7 | 21.1 |
| Disruptive behaviour | 43.9 | 44.1 | 23.4 | 23.3 |
| Learning or communication | 34.8 | 39.5 | 19.9 | 21.4 |
| Autism spectrum | 35.6 | 38.2 | 19.3 | 20.9 |
| Substance related | 53.5 | 57.7 | 30.3 | 30.9 |
| Schizophrenia/psychotic | 52.7 | 59.1 | 28.0 | 36.5 |
| Mood | 76.0 | 70.4 | 48.7 | 42.9 |
| Anxiety | 49.3 | 51.6 | 27.5 | 29.6 |
| Eating | 64.2 | 67.1 | 43.4 | 47.4 |
| Sleep | 42.0 | 50.1 | 26.1 | 30.1 |
| Adjustment | 73.8 | 66.6 | 53.7 | 43.3 |
aAmong assessments with this diagnosis, this is the proportion reaching this RiSsK threshold