Literature DB >> 32076752

[Cost analysis of inpatient versus outpatient intravenous antibiotic treatment for periprosthetic joint infections : A simulation].

Christoph Kolja Boese1, Philipp Lechler2,3, Michael Frink3, Michael Hackl4, Peer Eysel4, Christian Ries5.   

Abstract

BACKGROUND: Parenteral antibiotic administration in the treatment of periprosthetic joint infections (PJI) often requires inpatient settings. This is associated with significant costs to the healthcare system.
OBJECTIVE: The costs of inpatient parenteral antibiotic treatment (IPAT) and simulated costs of outpatient parenteral antibiotic treatment (OPAT) were compared in patients with PJI. Evaluations were carried out from the perspectives of cost bearers (insurances) and healthcare providers (hospitals).
MATERIAL AND METHODS: The analysis and simulations were performed for all cases with the ICD-10 diagnosis T84 in the treatment year 2015.
RESULTS: The simulated reduction of 159 bed-days in the 12 patients included in the study resulted in a reduction of the total costs of>18,000 € from the perspective of the health insurance. From the perspective of the hospitals the pure proceeds were improved by >22,000 €. The total costs of OPAT were >57,000 € for the health insurance. For hospitals the difference of policlinic proceeds and costs of OPAT showed a loss of >1500 €.
CONCLUSION: For hospitals the OPAT is overall financially advantageous. Further advantages due to opportunity costs seem to be interesting. For cost bearers OPAT is associated with an additional financial expenditure, particularly due to costs of outpatient medication. The private sector should be considered due to the assumed additional burden as well as the assumed patient comfort.

Entities:  

Keywords:  Cost calculation; Healthcare costs; Opportunity costs; Pure proceeds; Total costs

Mesh:

Substances:

Year:  2021        PMID: 32076752      PMCID: PMC7862513          DOI: 10.1007/s00132-020-03889-6

Source DB:  PubMed          Journal:  Orthopade        ISSN: 0085-4530            Impact factor:   1.087


  14 in total

Review 1.  Good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults in the UK: a consensus statement.

Authors:  Ann L N Chapman; R Andrew Seaton; Mike A Cooper; Sara Hedderwick; Vicky Goodall; Corienne Reed; Frances Sanderson; Dilip Nathwani
Journal:  J Antimicrob Chemother       Date:  2012-01-31       Impact factor: 5.790

2.  Complications associated with outpatient parenteral antibiotic therapy in children.

Authors:  Jennifer Le; Michael San Agustin; Elvin A Hernandez; Tu T Tran; Felice C Adler-Shohet
Journal:  Clin Pediatr (Phila)       Date:  2010-08-19       Impact factor: 1.168

3.  Patient satisfaction in an outpatient parenteral antimicrobial therapy (OPAT) unit practising predominantly self-administration of antibiotics with elastomeric pumps.

Authors:  L Saillen; L Arensdorff; E Moulin; R Voumard; C Cochet; N Boillat-Blanco; C Gardiol; S de Vallière
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2017-03-11       Impact factor: 3.267

Review 4.  Outpatient parenteral antimicrobial therapy today.

Authors:  Joseph A Paladino; Donald Poretz
Journal:  Clin Infect Dis       Date:  2010-09-15       Impact factor: 9.079

5.  A national survey of infectious disease practitioners on their use of outpatient parenteral antimicrobial therapy (OPAT).

Authors:  Eavan G Muldoon; Karen Switkowski; Alan Tice; David R Snydman; Geneve M Allison
Journal:  Infect Dis (Lond)       Date:  2014-11-21

6.  Risk Factors for Complications during Outpatient Parenteral Antimicrobial Therapy for Adult Orthopedic and Neurosurgical Infections.

Authors:  Kimberly K Felder; Lynn M Marshall; Louise E Vaz; Penelope D Barnes
Journal:  South Med J       Date:  2016-01       Impact factor: 0.954

7.  Outpatient parenteral antibiotic therapy for bone and joint infections: an italian multicenter study.

Authors:  S Esposito; S Leone; S Noviello; F Ianniello; M Fiore; M Russo; G Foti; M S Carpentieri; C Cellesi; G Zanelli; A Cellini; C Girmenia; F De Lalla; A Maiello; P Maio; F Marranconi; S Sabbatani; M Pantaleoni; F Ghinelli; M L Soranzo; P Vigano; T Re; P Viale; L Scudeller; F Scaglione; V Vullo
Journal:  J Chemother       Date:  2007-08       Impact factor: 1.714

8.  Outcomes of osteomyelitis among patients treated with outpatient parenteral antimicrobial therapy.

Authors:  Alan D Tice; Pamela A Hoaglund; David A Shoultz
Journal:  Am J Med       Date:  2003-06-15       Impact factor: 4.965

9.  Cost-analysis of inpatient and outpatient parenteral antimicrobial therapy in orthopaedics: A systematic literature review.

Authors:  Christoph Kolja Boese; Philipp Lechler; Michael Frink; Michael Hackl; Peer Eysel; Christian Ries
Journal:  World J Clin Cases       Date:  2019-07-26       Impact factor: 1.337

10.  Outpatient parenteral antimicrobial therapy with ceftriaxone for acute tonsillopharyngitis: efficacy, patient satisfaction, cost effectiveness, and safety.

Authors:  Samah Al Alawi; Somaya Abdulkarim; Hazem Elhennawy; Anwar Al-Mansoor; Ahmed Al Ansari
Journal:  Infect Drug Resist       Date:  2015-08-07       Impact factor: 4.003

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