Gêisa-Aiane-de Morais Sampaio1, Izaura-Helena-Chaves de Meneses1, Fabiola-Galbiatti de Carvalho2, Hugo-Lemes Carlo3, Eliseu-Aldrighi Münchow3, Taís-de Souza Barbosa2, Matheus-Melo Pithon4, Polliana-Muniz Alves5, Rogério Lacerda-Santos2. 1. DDS. M.Sc. Department of Clinical and Social Dentistry, Dental School, Federal University of Paraíba, João Pessoa, Paraíba, Brazil. 2. DDS., M.Sc., Ph.D. Professor. Department of Orthodontics and Pediatric Dentistry, Dental School, Federal University of de Fora, Governador Valadares, Minas Gerais, Brazil. 3. DDS., M.Sc., Ph.D. Professor. Department of Restorative Dentistry, Dental School, Federal University of de Fora, Governador Valadares, Minas Gerais, Brazil. 4. DDS., M.Sc., Ph.D. Professor. Department of Orthodontics, Dental School, State University of the Southwest of Bahia, Jéquie, Bahia, Brazil. 5. DDS., M.Sc., Ph.D. Professor. Department of Patology, Dental School, State University of Paraíba, Campina Grande, Paraíba, Brazil.
Abstract
BACKGROUND: The focus of this study was to evaluate the antimicrobial, mechanical properties and biocompatibility of glass ionomer (GICs) modified by Chlorhexidine (CHX). MATERIAL AND METHODS: For biocompatibility, 105 male Wistar rats were used, divided into 7 groups (n=15): Group C (Control,Polyethylene), Groups M, M10, M18, and Groups RL, RL10, RL18 (M-Meron and RL-Riva Luting: conventional, and modified with 10%, and 18% CHX, respectively). The tissues were analyzed under optical microscope for different cellular events and time intervals. Antibacterial effect and Shear Bond Strength Test (SBST) were also analyzed. Biocompatibility was analyzed by the Kruskal-Wallis and Dunn tests; SBST one-way ANOVA and Tukey test (P<0.05). For the antibacterial effect, the Kruskal-Wallis and Friedman, followed by Dunn (P<0.05) tests were used. RESULTS: Morphological study of the tissues showed inflammatory infiltrate with significant differences between Groups C and RL18, in the time intervals of 7(P=0.013) and 15(P=0.032) days. The antimicrobial effects of the cements was shown to be CHX concentration-dependent (P=0.001). The SBST showed no significant difference between the Groups of Meron cement (P=0.385), however, there was difference between Group RL and Groups RL10 and RL18 (P=0.001). CONCLUSIONS: The addition of CHX did not negatively influence the SBST. Meron-CHX-10% was the most biocompatible, and Riva-CHX-18% had more influence on the inflammatory process and presented slower tissue repair. Key words:Glass ionomer, chlorhexidine, biocompatibility, antimicrobial properties, microscope. Copyright:
BACKGROUND: The focus of this study was to evaluate the antimicrobial, mechanical properties and biocompatibility of glass ionomer (GICs) modified by Chlorhexidine (CHX). MATERIAL AND METHODS: For biocompatibility, 105 male Wistar rats were used, divided into 7 groups (n=15): Group C (Control,Polyethylene), Groups M, M10, M18, and Groups RL, RL10, RL18 (M-Meron and RL-Riva Luting: conventional, and modified with 10%, and 18% CHX, respectively). The tissues were analyzed under optical microscope for different cellular events and time intervals. Antibacterial effect and Shear Bond Strength Test (SBST) were also analyzed. Biocompatibility was analyzed by the Kruskal-Wallis and Dunn tests; SBST one-way ANOVA and Tukey test (P<0.05). For the antibacterial effect, the Kruskal-Wallis and Friedman, followed by Dunn (P<0.05) tests were used. RESULTS: Morphological study of the tissues showed inflammatory infiltrate with significant differences between Groups C and RL18, in the time intervals of 7(P=0.013) and 15(P=0.032) days. The antimicrobial effects of the cements was shown to be CHX concentration-dependent (P=0.001). The SBST showed no significant difference between the Groups of Meron cement (P=0.385), however, there was difference between Group RL and Groups RL10 and RL18 (P=0.001). CONCLUSIONS: The addition of CHX did not negatively influence the SBST. Meron-CHX-10% was the most biocompatible, and Riva-CHX-18% had more influence on the inflammatory process and presented slower tissue repair. Key words:Glass ionomer, chlorhexidine, biocompatibility, antimicrobial properties, microscope. Copyright:
Authors: Rogério Lacerda-Santos; Berthiene M S Roberto; Bruna de Siqueira Nunes; Fabiola G Carvalho; Antonielson Dos Santos; Antônio F M Dantas Journal: Microsc Res Tech Date: 2019-03-29 Impact factor: 2.769
Authors: Marcel M Farret; Eduardo Martinelli de Lima; Eduardo G Mota; Hugo M S Oshima; Valdir Barth; Silvia D de Oliveira Journal: Angle Orthod Date: 2011-02-07 Impact factor: 2.079
Authors: José Lucas Dos Santos Araújo; Mariana Massi Afonso Alvim; Márcio José da Silva Campos; Ana Carolina Morais Apolônio; Fabíola Galbiatti Carvalho; Rogério Lacerda-Santos Journal: Eur J Dent Date: 2021-08-24