Literature DB >> 32070225

APOE4 Accelerates Development of Dementia After Stroke: Is There a Role for Cerebrovascular Dysfunction?

Axel Montagne1, Daniel A Nation1,2,3,4, Berislav V Zlokovic1,2.   

Abstract

Entities:  

Keywords:  apolipoprotein E4; blood-brain barrier; cyclophilin A; dementia; stroke

Mesh:

Substances:

Year:  2020        PMID: 32070225      PMCID: PMC7041876          DOI: 10.1161/STROKEAHA.119.028814

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


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  16 in total

1.  Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.

Authors:  Robert D Bell; Ethan A Winkler; Itender Singh; Abhay P Sagare; Rashid Deane; Zhenhua Wu; David M Holtzman; Christer Betsholtz; Annika Armulik; Jan Sallstrom; Bradford C Berk; Berislav V Zlokovic
Journal:  Nature       Date:  2012-05-16       Impact factor: 49.962

2.  Pericytes regulate the blood-brain barrier.

Authors:  Annika Armulik; Guillem Genové; Maarja Mäe; Maya H Nisancioglu; Elisabet Wallgard; Colin Niaudet; Liqun He; Jenny Norlin; Per Lindblom; Karin Strittmatter; Bengt R Johansson; Christer Betsholtz
Journal:  Nature       Date:  2010-10-13       Impact factor: 49.962

3.  Microvascular injury and blood-brain barrier leakage in Alzheimer's disease.

Authors:  B D Zipser; C E Johanson; L Gonzalez; T M Berzin; R Tavares; C M Hulette; M P Vitek; V Hovanesian; E G Stopa
Journal:  Neurobiol Aging       Date:  2006-06-16       Impact factor: 4.673

4.  Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.

Authors:  Axel Montagne; Angeliki M Nikolakopoulou; Zhen Zhao; Abhay P Sagare; Gabriel Si; Divna Lazic; Samuel R Barnes; Madelaine Daianu; Anita Ramanathan; Ariel Go; Erica J Lawson; Yaoming Wang; William J Mack; Paul M Thompson; Julie A Schneider; Jobin Varkey; Ralf Langen; Eric Mullins; Russell E Jacobs; Berislav V Zlokovic
Journal:  Nat Med       Date:  2018-02-05       Impact factor: 53.440

5.  Effect of APOE genotype on microvascular basement membrane in Alzheimer's disease.

Authors:  S Salloway; T Gur; T Berzin; R Tavares; B Zipser; S Correia; V Hovanesian; J Fallon; V Kuo-Leblanc; D Glass; C Hulette; C Rosenberg; M Vitek; E Stopa
Journal:  J Neurol Sci       Date:  2002-11-15       Impact factor: 3.181

6.  The APOE ɛ4/ɛ4 genotype potentiates vascular fibrin(ogen) deposition in amyloid-laden vessels in the brains of Alzheimer's disease patients.

Authors:  Karin Hultman; Sidney Strickland; Erin H Norris
Journal:  J Cereb Blood Flow Metab       Date:  2013-05-08       Impact factor: 6.200

7.  APOE-ε4 Genotype and Dementia Before and After Transient Ischemic Attack and Stroke: Population-Based Cohort Study.

Authors:  Sarah T Pendlebury; Debbie Poole; Annette Burgess; Julia Duerden; Peter M Rothwell
Journal:  Stroke       Date:  2020-02-18       Impact factor: 7.914

8.  Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction.

Authors:  Vladimir V Senatorov; Aaron R Friedman; Dan Z Milikovsky; Jonathan Ofer; Rotem Saar-Ashkenazy; Adiel Charbash; Naznin Jahan; Gregory Chin; Eszter Mihaly; Jessica M Lin; Harrison J Ramsay; Ariana Moghbel; Marcela K Preininger; Chelsy R Eddings; Helen V Harrison; Rishi Patel; Yishuo Shen; Hana Ghanim; Huanjie Sheng; Ronel Veksler; Peter H Sudmant; Albert Becker; Barry Hart; Michael A Rogawski; Andrew Dillin; Alon Friedman; Daniela Kaufer
Journal:  Sci Transl Med       Date:  2019-12-04       Impact factor: 17.956

9.  Pericytes are required for blood-brain barrier integrity during embryogenesis.

Authors:  Richard Daneman; Lu Zhou; Amanuel A Kebede; Ben A Barres
Journal:  Nature       Date:  2010-10-13       Impact factor: 49.962

10.  Incidence and prevalence of dementia associated with transient ischaemic attack and stroke: analysis of the population-based Oxford Vascular Study.

Authors:  Sarah T Pendlebury; Peter M Rothwell
Journal:  Lancet Neurol       Date:  2019-02-12       Impact factor: 59.935

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  8 in total

Review 1.  APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases.

Authors:  Rosalía Fernández-Calle; Sabine C Konings; Javier Frontiñán-Rubio; Juan García-Revilla; Lluís Camprubí-Ferrer; Martina Svensson; Isak Martinson; Antonio Boza-Serrano; José Luís Venero; Henrietta M Nielsen; Gunnar K Gouras; Tomas Deierborg
Journal:  Mol Neurodegener       Date:  2022-09-24       Impact factor: 18.879

Review 2.  Neurovascular Dysfunction in Diverse Communities With Health Disparities-Contributions to Dementia and Alzheimer's Disease.

Authors:  Napatsorn Saiyasit; Evan-Angelo R Butlig; Samantha D Chaney; Miranda K Traylor; Nanako A Hawley; Ryleigh B Randall; Hanna V Bobinger; Carl A Frizell; Franklin Trimm; Errol D Crook; Mike Lin; Benjamin D Hill; Joshua L Keller; Amy R Nelson
Journal:  Front Neurosci       Date:  2022-06-29       Impact factor: 5.152

3.  APOE ε4 and exercise interact in a sex-specific manner to modulate dementia risk factors.

Authors:  Kate E Foley; Cory A Diemler; Amanda A Hewes; Dylan T Garceau; Michael Sasner; Gareth R Howell
Journal:  Alzheimers Dement (N Y)       Date:  2022-06-29

4.  Clinical Significance and Value of Serum Homocysteine and Urine 11 Dehydrothromboxane B2 Combined with Transferrin-Specific Peptide in the Diagnosis of Cerebral Apoplexy.

Authors:  Junli Liu; Juan He; Chang Zhang
Journal:  Comput Math Methods Med       Date:  2022-05-17       Impact factor: 2.809

5.  ApoE4 Astrocytes Secrete Basement Membranes Rich in Fibronectin and Poor in Laminin Compared to ApoE3 Astrocytes.

Authors:  Abby Keable; Ronan O'Neill; Matthew MacGregor Sharp; Maureen Gatherer; Ho Ming Yuen; David Annandale Johnston; Roy Oliver Weller; Roxana Octavia Carare
Journal:  Int J Mol Sci       Date:  2020-06-19       Impact factor: 5.923

Review 6.  Blood-brain barrier disruption in atrial fibrillation: a potential contributor to the increased risk of dementia and worsening of stroke outcomes?

Authors:  Ritambhara Aryal; Adjanie Patabendige
Journal:  Open Biol       Date:  2021-04-21       Impact factor: 6.411

7.  Cholesterol, Atherosclerosis, and APOE in Vascular Contributions to Cognitive Impairment and Dementia (VCID): Potential Mechanisms and Therapy.

Authors:  Michael Tran Duong; Ilya M Nasrallah; David A Wolk; Catherine C Y Chang; Ta-Yuan Chang
Journal:  Front Aging Neurosci       Date:  2021-03-25       Impact factor: 5.750

8.  Systemic infection exacerbates cerebrovascular dysfunction in Alzheimer's disease.

Authors:  Daniel Asby; Delphine Boche; Stuart Allan; Seth Love; J Scott Miners
Journal:  Brain       Date:  2021-07-28       Impact factor: 13.501

  8 in total

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