Bo Lan1, Shiyu Jiang1, Tao Li2, Xiaoying Sun3, Fei Ma4. 1. Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. 2. Department of psychological medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. 3. Department of Medical Oncology, Cancer Hospital of HuanXing ChaoYang District, Beijing, China. 4. Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address: drmafei@126.com.
Abstract
BACKGROUND: It has been reported that younger breast cancer patients are at greater risk of having psychological problems than their older counterparts. This study is conducted to evaluate the psychological status of Chinese postoperative breast cancer patients aged 35 years or younger and understand the associated factors in this patient group. METHODS: This cross-sectional study prospectively enrolled 114 Chinese postoperative breast cancer patients aged 35 years or younger. They completed standard instruments evaluating depression (Patient Health Questionnaire [PHQ]-9) and anxiety (General Anxiety Disorder-7). Logistic regression was used to identify the associated factors. RESULTS: The mean scores were 5.21 and 4.19 for the PHQ-9 and General Anxiety Disorder-7, respectively. There were 76.3%, 20.2%, and 3.5% patients categorized into the none and/or mild (score 1-7), moderate (score 8-14), and moderate to severe depression (score 15-19) groups, respectively. For anxiety, there were 91.2%, 5.3% and, 3.5% of patients in the none and/or mild anxiety (score 0-9), moderate anxiety (score 10-14), and severe anxiety (score 15-21) groups, respectively. With univariate analysis, cohabitation status (P = 0.002) and adjuvant endocrine therapy (P = 0.048) tended to be associated with the level of depression (PHQ-9 ≥ 8). In the multivariate analysis, living alone (odds ratio = 5.08, 95% confidence interval = 1.81-14.26, P = 0.002) and the administration of ovarian function suppression (odds ratio = 2.76, 95% confidence interval = 1.04-7.37, P = 0.042) were still independently correlated with a higher level of depression. No significant predictors were found for anxiety. CONCLUSIONS: Our study evaluated the depression and anxiety of young Chinese breast cancer patients; addressing the psychosocial assessment of these patients should be integrated into cancer treatments and follow-ups, especially for those receiving ovarian function suppression and living alone.
BACKGROUND: It has been reported that younger breast cancerpatients are at greater risk of having psychological problems than their older counterparts. This study is conducted to evaluate the psychological status of Chinese postoperative breast cancerpatients aged 35 years or younger and understand the associated factors in this patient group. METHODS: This cross-sectional study prospectively enrolled 114 Chinese postoperative breast cancerpatients aged 35 years or younger. They completed standard instruments evaluating depression (Patient Health Questionnaire [PHQ]-9) and anxiety (General Anxiety Disorder-7). Logistic regression was used to identify the associated factors. RESULTS: The mean scores were 5.21 and 4.19 for the PHQ-9 and General Anxiety Disorder-7, respectively. There were 76.3%, 20.2%, and 3.5% patients categorized into the none and/or mild (score 1-7), moderate (score 8-14), and moderate to severe depression (score 15-19) groups, respectively. For anxiety, there were 91.2%, 5.3% and, 3.5% of patients in the none and/or mild anxiety (score 0-9), moderate anxiety (score 10-14), and severe anxiety (score 15-21) groups, respectively. With univariate analysis, cohabitation status (P = 0.002) and adjuvant endocrine therapy (P = 0.048) tended to be associated with the level of depression (PHQ-9 ≥ 8). In the multivariate analysis, living alone (odds ratio = 5.08, 95% confidence interval = 1.81-14.26, P = 0.002) and the administration of ovarian function suppression (odds ratio = 2.76, 95% confidence interval = 1.04-7.37, P = 0.042) were still independently correlated with a higher level of depression. No significant predictors were found for anxiety. CONCLUSIONS: Our study evaluated the depression and anxiety of young Chinese breast cancerpatients; addressing the psychosocial assessment of these patients should be integrated into cancer treatments and follow-ups, especially for those receiving ovarian function suppression and living alone.
Authors: Yanyan Li; Hong Liu; Yaoyao Sun; Jie Li; Yanhong Chen; Xuan Zhang; Juan Wang; Liuliu Wu; Di Shao; Fenglin Cao Journal: AIMS Public Health Date: 2021-10-20
Authors: Katarina Veličković; Carl A K Borrebaeck; Pär-Ola Bendahl; Cecilia Hegardt; Per Johnsson; Corinna Richter; Lisa Rydén; Ingalill Rahm Hallberg Journal: Front Oncol Date: 2022-08-16 Impact factor: 5.738