Greta Hollis1, Robert Franz2, Judy Bauer3, Jack Bell1,3,4. 1. The Prince Charles Hospital, Brisbane, Australia. 2. Department of General Surgery, The Prince Charles Hospital, Brisbane, Australia. 3. School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, Queensland, Australia. 4. Allied Health Research Collaborative, Metro North Hospital and Health Service, Brisbane, Australia.
Abstract
AIM: The present article aimed to evaluate the feasibility of implementing a very low calorie diet (VLCD) weight loss program into the pre-operative model of care for elective general surgery patients with obesity. METHODS: A prospective, randomised control trial of adults with obesity awaiting elective general surgery was conducted at an outpatient clinic at a tertiary hospital. Patients were randomised to the intervention group, an 8-week VLCD program incorporating Optifast (Nestle Health, Germany) shakes, or to standard care (generic healthy eating information). Data were collected at baseline, week 8 and at 30 days post-surgery. The primary outcome of the study was feasibility, which was evaluated through demand, practicality, integration and acceptability measures. RESULTS:Forty-six participants (M 17: F 29, mean age 51.6 (13.1) years) with a mean body mass index ≥ 30 kg/m2 (40.5 kg/m2 (5.9)) were recruited. Of participants who completed the study there was a higher mean weight loss in the intervention group compared to the control group (-6.5 vs +0.15 kg; P = <.001), with no excessive loss of muscle mass (MM), measured by bioelectrical impedance analysis. The reduction in waist circumference was greater for the intervention compared to control group (-6.11 vs +1.36 cm; P = .003). Quality of life increased significantly in the intervention group (P < .001). CONCLUSIONS: The pre-operative VLCD program produced clinically meaningful rapid weight loss pre-surgery and improved quality of life without an excessive loss of MM.
RCT Entities:
AIM: The present article aimed to evaluate the feasibility of implementing a very low calorie diet (VLCD) weight loss program into the pre-operative model of care for elective general surgery patients with obesity. METHODS: A prospective, randomised control trial of adults with obesity awaiting elective general surgery was conducted at an outpatient clinic at a tertiary hospital. Patients were randomised to the intervention group, an 8-week VLCD program incorporating Optifast (Nestle Health, Germany) shakes, or to standard care (generic healthy eating information). Data were collected at baseline, week 8 and at 30 days post-surgery. The primary outcome of the study was feasibility, which was evaluated through demand, practicality, integration and acceptability measures. RESULTS: Forty-six participants (M 17: F 29, mean age 51.6 (13.1) years) with a mean body mass index ≥ 30 kg/m2 (40.5 kg/m2 (5.9)) were recruited. Of participants who completed the study there was a higher mean weight loss in the intervention group compared to the control group (-6.5 vs +0.15 kg; P = <.001), with no excessive loss of muscle mass (MM), measured by bioelectrical impedance analysis. The reduction in waist circumference was greater for the intervention compared to control group (-6.11 vs +1.36 cm; P = .003). Quality of life increased significantly in the intervention group (P < .001). CONCLUSIONS: The pre-operative VLCD program produced clinically meaningful rapid weight loss pre-surgery and improved quality of life without an excessive loss of MM.
Authors: Natalie Pavlovic; Robert A Boland; Bernadette Brady; Furkan Genel; Ian A Harris; Victoria M Flood; Justine M Naylor Journal: Clin Obes Date: 2021-08-31
Authors: Rachel Perry; Georgia Herbert; Charlotte Atkinson; Clare England; Kate Northstone; Sarah Baos; Tim Brush; Amanda Chong; Andy Ness; Jessica Harris; Anne Haase; Sanjoy Shah; Maria Pufulete Journal: BMJ Open Date: 2021-09-30 Impact factor: 3.006