Literature DB >> 32067266

A fluorination method for measuring the 13 C-13 C isotopologue of C2 molecules.

Koudai Taguchi1, Tomonari Yamamoto1, Mayuko Nakagawa1,2, Alexis Gilbert1,2, Yuichiro Ueno1,2,3.   

Abstract

RATIONALE: Doubly substituted isotope species ("clumped" isotopes) can provide insights into the biogeochemical history of a molecule, including its temperature of formation and/or its (bio)synthetic pathway. Here, we propose a new fluorination method for the measurement of 13 C-13 C species in C2 molecules using a conventional isotope ratio mass spectrometer. Target molecules include ethane, ethene and ethanol.
METHODS: 13 C-13 C isotope species in C2 molecules were measured as C2 F6 using a conventional isotope ratio mass spectrometer. Ethane and ethene are directly fluorinated to C2 F6 . Ethanol is measured after dehydration to ethene and subsequent fluorination of the latter. The method enables the measurement of the Δ13 C13 C values normalized against a reference working standard.
RESULTS: The reproducibility of the whole protocol, including chemical modification steps and measurement of C2 F6 isotopologues, is better than ±0.14‰ for all the compounds. Ethane from natural gas samples and biologically derived ethanol show a narrow range of Δ13 C13 C values, varying from 0.72‰ to 0.90‰. In contrast, synthetic ethanol as well as putative abiotic ethane show Δ13 C13 C values significantly different from this range with values of 1.14‰ and 0.25‰, respectively.
CONCLUSIONS: The method presented here provides alternative means of measuring 13 C-13 C species to that using high-resolution mass spectrometry. Preliminary data from natural and synthetic molecules re-emphasizes the potential of 13 C clumped isotope species as a (bio)marker.
© 2020 John Wiley & Sons, Ltd.

Entities:  

Year:  2020        PMID: 32067266     DOI: 10.1002/rcm.8761

Source DB:  PubMed          Journal:  Rapid Commun Mass Spectrom        ISSN: 0951-4198            Impact factor:   2.419


  2 in total

1.  Hydrocarbon Cycling in the Tokamachi Mud Volcano (Japan): Insights from Isotopologue and Metataxonomic Analyses.

Authors:  Alexis Gilbert; Mayuko Nakagawa; Koudai Taguchi; Naizhong Zhang; Akifumi Nishida; Naohiro Yoshida
Journal:  Microorganisms       Date:  2022-07-14

2.  Low 13C-13C abundances in abiotic ethane.

Authors:  Koudai Taguchi; Alexis Gilbert; Barbara Sherwood Lollar; Thomas Giunta; Christopher J Boreham; Qi Liu; Juske Horita; Yuichiro Ueno
Journal:  Nat Commun       Date:  2022-10-02       Impact factor: 17.694

  2 in total

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