| Literature DB >> 32065751 |
Bao Qiong Li1, Zong-Wang Qiu1, Ai-Jun Ma1, Jin-Bao Peng1, Na Feng1, Ji-Yuan Du2, Han-Peng Pan1, Xiang-Zhi Zhang1, Xue-Tao Xu1.
Abstract
An efficient and straightforward Lewis-acid-mediated stereoselective (4 + 3)-cyclization of indole-substituted alkylidene malonates and donor-acceptor cyclopropanes has been developed involving the Friedel-Crafts/Michael addition cyclization cascade. This reaction provides a mild and effective method for the construction of synthetically and structurally interesting functionalized cycloheptannelated indoles.Entities:
Year: 2020 PMID： 32065751 DOI： 10.1021/acs.orglett.0c00248
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005