Literature DB >> 32064200

Metastatic Mucinous Adenocarcinoma of the Cervix Presenting as Acute Hepatitis.

Shanker Kundumadam1, Hansini Laharwani2, Shafeek Azhikkalayil3, Gokul Das4.   

Abstract

Cervical cancer is well known to cause metastasis in liver. Not usually they present in a pattern of acute hepatitis with the liver enzymes trending above the range of thousands. Here we present an interesting case of a patient who presented as acute hepatitis in the setting of metastatic cervical cancer to the liver. She presented with elevated liver enzymes above thousands. Her imaging studies revealed new metastatic lesions in the liver. She was subsequently started on chemotherapy but unfortunately, two months later developed septic shock and expired. To our knowledge this is the only case describing a malignancy with metastasis to the liver presenting as an acute hepatitis picture. All the other cases that have been described in the literature presented with acute liver failure.
Copyright © 2020, Kundumadam et al.

Entities:  

Keywords:  acute hepatitis; cervical cancer; metastatic cervical cancer

Year:  2020        PMID: 32064200      PMCID: PMC7008751          DOI: 10.7759/cureus.6620

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  5 in total

1.  Acute liver failure secondary to hepatic infiltration: a single centre experience of 18 cases.

Authors:  D Rowbotham; J Wendon; R Williams
Journal:  Gut       Date:  1998-04       Impact factor: 23.059

2.  Fulminant hepatic failure resulting from small-cell lung cancer and dramatic response of chemotherapy.

Authors:  Kyoichi Kaira; Atsushi Takise; Rieko Watanabe; Masatomo Mori
Journal:  World J Gastroenterol       Date:  2006-04-21       Impact factor: 5.742

3.  Annual report of the Committee on Gynecologic Oncology, the Japan Society of Obstetrics and Gynecology.

Authors:  Wataru Yamagami; Daisuke Aoki
Journal:  J Obstet Gynaecol Res       Date:  2014-11-05       Impact factor: 1.730

4.  Metastatic prostatic carcinoma presenting as fulminant hepatic failure.

Authors:  Faiz A Shakir; Mohammed Madhoun; Joshua Whorton; Richard Harty
Journal:  South Med J       Date:  2008-10       Impact factor: 0.954

Review 5.  Elevated Liver Enzymes in Asymptomatic Patients - What Should I Do?

Authors:  Mazyar Malakouti; Archish Kataria; Sayed K Ali; Steven Schenker
Journal:  J Clin Transl Hepatol       Date:  2017-09-21
  5 in total

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